Early pirfenidone treatment enhances lung function in idiopathic pulmonary fibrosis patients

doi:10.12998/wjcc.v12.i28.6247

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Oct 6, 2024 (publication date) through Aug 13, 2024

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Letter to the Editor

World J Clin Cases. Oct 6, 2024; 12(28): 6247-6249
Published online Oct 6, 2024. doi: 10.12998/wjcc.v12.i28.6247

Early pirfenidone treatment enhances lung function in idiopathic pulmonary fibrosis patients

Jin-Wei Zhang

Jin-Wei Zhang, Medical School, University of Exeter, Exeter EX4 4PS, United Kingdom

Author contributions: Zhang JW designed the overall concept and outline of the manuscript; Zhang JW contributed to the discussion and design of the manuscript; Zhang JW contributed to the writing and editing of the manuscript, illustrations, and review of the literature.

Conflict-of-interest statement: The authors declare that they have no conflict of interest.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: Https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Jin-Wei Zhang, BSc, MSc, PhD, Academic Editor, Professor, Senior Editor, Medical School, University of Exeter, Stocker Rd, Exeter EX4 4PS, United Kingdom. j.zhang5@exeter.ac.uk

Received: June 29, 2024
Revised: July 25, 2024
Accepted: July 30, 2024
Published online: October 6, 2024
Processing time: 44 Days and 18.9 Hours

Core Tip

Core Tip: Early intervention with pirfenidone in idiopathic pulmonary fibrosis (IPF) patients significantly improves lung function, reduces inflammation, enhances physical endurance, and decreases adverse reactions. These findings underscore the potential of early pirfenidone treatment to alter the disease course and improve patient outcomes, emphasizing its importance in clinical management strategies for IPF.