Incidental renal cell carcinoma post bilateral nephrectomy in autosomal dominant polycystic kidney disease

doi:10.12998/wjcc.v12.i28.6187

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Oct 6, 2024 (publication date) through Aug 13, 2024

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Oct 6, 2024; 12(28): 6187-6194
Published online Oct 6, 2024. doi: 10.12998/wjcc.v12.i28.6187

Incidental renal cell carcinoma post bilateral nephrectomy in autosomal dominant polycystic kidney disease

Min-Ho Shin, Nam-Kyu Choi

Min-Ho Shin, Nam-Kyu Choi, Division of General Surgery, Department of Hepato-Bilio-Pancreatic Surgery and Transplantation Surgery, Chosun University College of Medicine, Gwangju 61453, South Korea

Author contributions: Choi NK contributed to the design and implementation of the study; Shin MH contributed to the analysis of the results and to the writing of the manuscript.

Supported by The Research fund from the Chosun University Hospital, No. 2023-26.

Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of Chosun University Hospital in Gwangju, South Korea (No. 2023-04-009).

Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.

Conflict-of-interest statement: All authors have no conflict-of-interest.

Data sharing statement: No additional data are available.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: Https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Nam-Kyu Choi, MD, PhD, Professor, Division of General Surgery, Department of Hepato-Bilio-Pancreatic Surgery and Transplantation Surgery, Chosun University College of Medicine, No. 365 Pilmun-daero, Gwangju 61453, South Korea. cnk@chosun.ac.kr

Received: May 24, 2024
Revised: July 1, 2024
Accepted: July 15, 2024
Published online: October 6, 2024
Processing time: 80 Days and 5 Hours

Core Tip

Core Tip: Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder that leads to kidney and liver cysts, with a prevalence of 1 in 1000–2500 individuals. It often progresses to end-stage renal disease (ESRD). Incidence of renal cell carcinoma (RCC) is higher in patients with ADPKD than in the general population. Diagnosing RCC in ADPKD is challenging due to overlapping symptoms and distorted renal anatomy. In a study of 19 ADPKD patients undergoing nephrectomy, RCC was found in 21.1% of patients. The study highlights the need for vigilant RCC monitoring in patients with ADPKD, especially those with ESRD.