Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 16, 2024; 12(26): 5990-5997
Published online Sep 16, 2024. doi: 10.12998/wjcc.v12.i26.5990
Extragastrointestinal stromal tumors with diffuse membranous distribution with bleeding: A case report
Jian-Duo Xu, Zheng Wang, Qian Zhou, Ning Meng, Shu-Mei Zhang, Nan Liu
Jian-Duo Xu, Department of Gastrointestinal Surgery, Shijiazhuang People’s Hospital, Shijiazhuang 050000, Hebei Province, China
Zheng Wang, Shu-Mei Zhang, Nan Liu, Department of Gastroenterology, Shijiazhuang People's Hospital, Shijiazhuang 050000, Hebei Province, China
Qian Zhou, Ning Meng, Department of General Surgery, Shijiazhuang People's Hospital, Shijiazhuang 050000, Hebei Province, China
Author contributions: Xu JD designed the research; Wang Z performed the research; Meng N, Zhou Q, Zhang SM, and Liu N analyzed the data and wrote the manuscript; all authors have read and approved the final manuscript.
Informed consent statement: All patients and healthy volunteers provided written informed consent prior to their inclusion in the study.
Conflict-of-interest statement: The authors declare no competing interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: Https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zheng Wang, MD, Associate Chief Physician, Department of Gastroenterology, Shijiazhuang People's Hospital, No. 9 Fangbei Street, Shijiazhuang 050000, Hebei Province, China. wzcelia1983@163.com
Received: April 18, 2024
Revised: June 8, 2024
Accepted: July 3, 2024
Published online: September 16, 2024
Processing time: 95 Days and 16.6 Hours
Core Tip

Core Tip: Extragastrointestinal stromal tumors (EGIST) are less common in comparison with gastrointestinal stromal tumors. EGIST tumors in the membranous tissue are rare and tumors independently developing in membrane tissues such as greater omentum, mesentery or peritoneum are occasionally reported. Diffuse membranous tumor in entire abdominal cavity is extremely rare worldwide. We report a case of EGIST with the tumors like cobblestone being diffusely distributed in entire abdominal cavity accompanied by spontaneous bleeding. The tumors may not be fully resected by surgery, hence we made biopsy, pathological examination and gene detection to determine the therapy. Treatment with imatinib achieved better outcome.