Analysis of long-term outcome of modified gastric bypass for type 2 diabetes mellitus in Chinese patients

doi:10.12998/wjcc.v12.i25.5697

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Clin Cases. Sep 6, 2024; 12(25): 5697-5705
Published online Sep 6, 2024. doi: 10.12998/wjcc.v12.i25.5697

Analysis of long-term outcome of modified gastric bypass for type 2 diabetes mellitus in Chinese patients

Ying Xing, Ri-Xing Bai, You-Guo Li, Jun Xu, Zhi-Qiang Zhong, Ming Yan, Wen-Mao Yan

Ying Xing, Ri-Xing Bai, You-Guo Li, Jun Xu, Zhi-Qiang Zhong, Ming Yan, Wen-Mao Yan, Department of General Surgery, Beijing Tiantan Hospital, Beijing 100170, China

Author contributions: Xing Y write the article; Bai RX and Li YG performed the suegery; Xu J and Zhong ZQ managed the patients; Yan M collected data; Yan WM revised the article.

Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Beijing Tiantan Hospital, Approval No. KYSQ 2020-177-01.

Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrolment.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Data sharing statement: No additional data are available.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Wen-Mao Yan, MD, Surgeon, Department of General Surgery, Beijing Tiantan Hospital, No. 119 South Fourth Ring West Road, Fengtai District, Beijing 100170, China. ywmao_2000@163.com

Received: January 12, 2024
Revised: May 31, 2024
Accepted: July 4, 2024
Published online: September 6, 2024
Processing time: 185 Days and 18.3 Hours

Core Tip

Core Tip: We described a modified gastric bypass procedure, we report the effect of such procedure in Chinese patients with type 2 diabetes mellitus (T2DM) patients and data of it’s 5 year follow up data. We found that average weight and body mass index of all 37 patients were reduced to 67.1 ± 12.2 kg and 24.6 ± 3.9 kg/m² respectively, while fasting plasma glucose and glycated hemoglobin A1c also reduced to 6.5 ± 1.3 mmol/L and 6.5% ± 0.9% 5 years later. Complete remission rate of T2DM at was 29.7%. Blood lipid, liver and renal function were significantly improved, history of T2DM and fasting C-peptide were significant prognostic factors influencing complete remission of T2DM after Roux-en-Y gastric bypass.