Editorial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 26, 2024; 12(24): 5448-5451
Published online Aug 26, 2024. doi: 10.12998/wjcc.v12.i24.5448
Diagnostic challenges from conflicting results of tests and imaging
Run Yu
Run Yu, Division of Endocrinology, Diabetes, and Metabolism, UCLA David Geffen School of Medicine, Los Angeles, CA 90095, United States
Author contributions: Yu R wrote the paper.
Conflict-of-interest statement: The author reports no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Run Yu, MD, PhD, Professor, Division of Endocrinology, Diabetes, and Metabolism, UCLA David Geffen School of Medicine, 200 Medical Plaza Driveway #530, Los Angeles, CA 90095, United States. runyu@mednet.ucla.edu
Received: February 25, 2024
Revised: May 13, 2024
Accepted: May 20, 2024
Published online: August 26, 2024
Processing time: 136 Days and 17.9 Hours
Core Tip

Core Tip: The underlying reason of challenging diagnoses is mostly conflicting data from history, tests, and imaging that point to different diagnoses. The case by Huffaker et al powerfully illustrates the occasional diagnostic challenges inherent in our current diagnostic approach and technology. Clinicians should realize that in rare situations, agnosticism in diagnosis is unavoidable but a treatment has to be initiated so long as the principle of primum non nocere is upheld.