Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 6, 2024; 12(22): 5245-5252
Published online Aug 6, 2024. doi: 10.12998/wjcc.v12.i22.5245
Concomitant atypical knee gout and seronegative rheumatoid arthritis: A case report
Zhou-Yi Chen, Min-Hua Ou-Yang, Shao-Wei Li, Rui Ou, Zhi-Huang Chen, Song Wei
Zhou-Yi Chen, Zhi-Huang Chen, Song Wei, Department of Chinese Medicine, General Hospital of Southern Theater Command, Guangzhou 510010, Guangdong Province, China
Min-Hua Ou-Yang, Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong Province, China
Shao-Wei Li, The Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong Province, China
Rui Ou, Department of Gout, Guangdong Hydropower Hospital, Guangzhou 511340, Guangdong Province, China
Author contributions: Chen ZY, Li SW, and Chen ZH crafted the research protocols for minimally invasive diagnostics and treatments and significantly contributed to the synthesis of case reports; Chen ZY, Ou R, Ou-Yang MH, and Wei S not only provided critical contributions to the clinical management of patients but also collected samples; Chen ZY, Ou-Yang MH, and Ou R analyzed patient medical records, synovial pathology, and joint fluid; Chen ZY and Li SW wrote the manuscript. All authors have read and approved the final manuscript.
Supported by Natural Science Foundation of Guangdong Province, No. 2023A1515011213.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist, and the manuscript was prepared and revised according to the CARE Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: Https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhi-Huang Chen, PhD, Professor, Department of Chinese Medicine, General Hospital of Southern Theater Command, No. 111 Liuhua Road, Yuexiu District, Guangzhou 510010, Guangdong Province, China. 18665032046@163.com
Received: April 15, 2024
Revised: June 11, 2024
Accepted: June 24, 2024
Published online: August 6, 2024
Processing time: 77 Days and 15.8 Hours
Core Tip

Core Tip: Addressing the rare co-occurrence of seronegative rheumatoid arthritis and atypical knee gout, this case reinforces the diagnostic and therapeutic challenges inherent in rheumatology. This highlights the necessity for clinicians to maintain a high degree of suspicion for atypical disease presentations and the importance of personalized, innovative treatment strategies. The successful outcome in this case, achieved through a combination of minimally invasive diagnostic techniques and a customized treatment plan, provides valuable insights for the effective management of similar complex cases.