Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 6, 2024; 12(22): 4992-4998
Published online Aug 6, 2024. doi: 10.12998/wjcc.v12.i22.4992
Clinical efficacy of gamma-oryzanol combined with Femoston for perimenopausal syndrome
Yang-Yang Kuang, Min-Qi Xiong, Jin-Xia Cai
Yang-Yang Kuang, Min-Qi Xiong, Jin-Xia Cai, Women's Health Management Center, Jiujiang Maternal and Child Health Hospital, Jiujiang 332000, Jiangxi Province, China
Author contributions: Kuang YY participated in the study design and wrote the manuscript; Kuang YY conducted the design of the study and reviewed/edited the drafts, and is guarantor; Kuang YY, Xiong MQ, and Cai JX collected and analyzed the data; Kuang YY revised the manuscript. All authors contributed to the article and approved the submitted article.
Institutional review board statement: This study was approved by the Ethic Committee of Jiujiang Maternal and Child Health Hospital.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All authors have no conflicts of interest to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yang-Yang Kuang, MM, Doctor, Women's Health Management Center, Jiujiang Maternal and Child Health Hospital, No. 61 Gantang South Road, Xunyang District, Jiujiang 332000, Jiangxi Province, China. 13576207600@163.com
Received: April 30, 2024
Revised: May 29, 2024
Accepted: June 14, 2024
Published online: August 6, 2024
Processing time: 62 Days and 21.8 Hours
Core Tip

Core Tip: Perimenopausal syndrome (PMS) is a chronic condition associated with estrogen deficiency. Hormone replacement therapy is the conventional treatment for PMS; however, because of possible adverse events such as stroke, breast cancer, endometrial cancer, glucose intolerance, and thromboembolic disease, its treatment alternatives must be continuously explored and optimized. Compared with Femoston monotherapy, proposed combination therapy of γ-oryzanol and Femoston has certain clinical advantages, including significantly better clinical efficacy, for treating patients with PMS. This treatment can prevent adverse reactions, actively regulate sex hormone levels, increase patient bone mineral density, and actively help improve sleep quality.