Meta-Analysis
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 26, 2024; 12(21): 4680-4690
Published online Jul 26, 2024. doi: 10.12998/wjcc.v12.i21.4680
Efficacy and safety of over-the-scope-clips in the therapy of acute nonvariceal upper gastrointestinal bleeding: Meta-analysis
Xue-Zhu Yang, Dan-Li Yu, Zhi Wang, Zhi-Long Gao
Xue-Zhu Yang, Dan-Li Yu, Zhi Wang, Department of Gastroendoscopy, Renmin Hospital, Hubei University of Medicine, Shiyan 442000, Hubei Province, China
Zhi-Long Gao, Department of Gastrointestinal Medicine III, Renmin Hospital, Hubei University of Medicine, Shiyan 442000, Hubei Province, China
Co-first authors: Xue-Zhu Yang and Dan-Li Yu.
Co-corresponding authors: Zhi Wang and Zhi-Long Gao.
Author contributions: Yang XZ and Yu DL contributed equally to this work as co-first authors; Wang Z and Gao ZL contributed equally to this work as co-corresponding authors; Yang XZ and Yu DL designed this study; Yang XZ, Yu DL, Wang Z and Gao ZL analyzed the data; Yang XZ and Yu DL wrote manuscript; and all authors read and approved the final manuscript.
Conflict-of-interest statement: Dr. Wang has nothing to disclose.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhi Wang, MM, Nurse, Department of Gastroendoscopy, Renmin Hospital, Hubei University of Medicine, No. 39 Chaoyang Middle Road, Shiyan 442000, Hubei Province, China. 16671498503@163.com
Received: March 4, 2024
Revised: May 10, 2024
Accepted: June 11, 2024
Published online: July 26, 2024
Processing time: 119 Days and 5.7 Hours
Core Tip

Core Tip: Upper gastrointestinal bleeding, especially Acute nonvariceal upper gastrointestinal bleeding (ANVUGIB) is a common life-threatening acute condition with high morbidity and mortality in gastroenterology. With the advancements in medical technology, a new endoscopic hemostatic technique, called the over-the-scope-clip (OTSC), is being used for ANVUGIB treatment. We performed a meta-analysis to study the role of OTSC in ANVUGIB treatment in terms of prevention of rebleeding, clinical success rate, procedure time, hospitalization time, and adverse events. We aim to determine whether OTSC could replace standard endoscopic treatment as a new generation of ANVUGIB treatment.