Observational Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 16, 2024; 12(20): 4206-4216
Published online Jul 16, 2024. doi: 10.12998/wjcc.v12.i20.4206
Metformin administration in prevention of colorectal polyps in type 2 diabetes mellitus patients
Xiao-Qing Wu, Li-Hua Deng, Qian Xue, Xia Li, Meng-Han Li, Jing-Tong Wang
Xiao-Qing Wu, Li-Hua Deng, Qian Xue, Xia Li, Meng-Han Li, Jing-Tong Wang, Department of Geriatrics, Peking University People's Hospital, Beijing 100044, China
Author contributions: Wu XQ contributed as the leader of project, development of research plan, sample collection, statistical analysis and writing the paper; Deng LH contributed to the data analysis review; Xue Q contributed the part of discussion and critical review; Li X and Li MH contributed to the critical review; Wang JT commented on previous versions of the manuscript and reviewed the final document; All authors perused and approved the final draft of this manuscript.
Supported by The International Institute of Population Health, Peking University Health Science Center, No. JKCJ202102; and The National Key Clinical Specialty Construction Projects, No. 2199000764.
Institutional review board statement: This study was reviewed and approved by the Ethics Review Committee of Peking University People's Hospital (Approval No. 2021B012-00).
Informed consent statement: All study participants provide informed written consent prior to study registration.
Conflict-of-interest statement: The authors declare having no conflicts of interest. The entities that funded this study were not associated in any way with the study design; data collection, analysis, and interpretation; or manuscript preparation; and did not enforce any restrictions related to the publication of this work.
Data sharing statement: The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jing-Tong Wang, Doctor, Deputy Director, Department of Geriatrics, Peking University People's Hospital, No. 11 Xizhimen South Street, Xicheng District, Beijing 100044, China. wangjingtong11@163.com
Received: March 10, 2024
Revised: May 7, 2024
Accepted: May 29, 2024
Published online: July 16, 2024
Processing time: 111 Days and 12.7 Hours
Core Tip

Core Tip: Studies have shown that oral metformin can safely and effectively reduce the incidence of colorectal adenomas. There is also literature suggesting that metformin has potential efficacy in preventing the development of colonic polyps in patients with acromegaly.