Kim CS, Choi CH, Yi KS, Kim Y, Lee J, Woo CG, Jeon YH. Absence of enhancement in a lesion does not preclude primary central nervous system T-cell lymphoma: A case report. World J Clin Cases 2024; 12(2): 374-382 [PMID: 38313636 DOI: 10.12998/wjcc.v12.i2.374]
Corresponding Author of This Article
Chi-Hoon Choi, MD, Professor, Department of Radiology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, 1 Chungdae-ro, Seowon-gu, Cheongju-si 28644, Chungcheongbuk-do, South Korea. chihoonc@chungbuk.ac.kr
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jan 16, 2024; 12(2): 374-382 Published online Jan 16, 2024. doi: 10.12998/wjcc.v12.i2.374
Absence of enhancement in a lesion does not preclude primary central nervous system T-cell lymphoma: A case report
Chan-Seop Kim, Chi-Hoon Choi, Kyung Sik Yi, Yook Kim, Jisun Lee, Chang Gok Woo, Young Hun Jeon
Chan-Seop Kim, Chi-Hoon Choi, Kyung Sik Yi, Yook Kim, Jisun Lee, Department of Radiology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju-si 28644, Chungcheongbuk-do, South Korea
Chang Gok Woo, Department of Pathology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju-si 28644, Chungcheongbuk-do, South Korea
Young Hun Jeon, Department of Radiology, Seoul National University Hosptial, Seoul 03080, South Korea
Author contributions: Kim CS, Choi CH, and Yi KS contributed to manuscript writing and editing and data collection; Kim CS contributed to data analysis; Kim CS, Choi CH, Yi KS, Kim Y, Lee J, Jeon YH and Woo CG contributed to conceptualization and supervision; All authors have read and approved the final manuscript.
Informed consent statement: Written informed consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read CARE Checklist (2016), and the manuscript was prepared and revised according to CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chi-Hoon Choi, MD, Professor, Department of Radiology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, 1 Chungdae-ro, Seowon-gu, Cheongju-si 28644, Chungcheongbuk-do, South Korea. chihoonc@chungbuk.ac.kr
Received: September 12, 2023 Peer-review started: September 12, 2023 First decision: November 30, 2023 Revised: December 12, 2023 Accepted: December 27, 2023 Article in press: December 27, 2023 Published online: January 16, 2024 Processing time: 121 Days and 0.8 Hours
Core Tip
Core Tip: The characteristic features of primary central nervous system T-cell lymphoma (PCNSTL) are not widely recognized owing to its low incidence rate. However, most malignant tumors demonstrate enhancement on gadolinium-enhanced magnetic resonance imaging (MRI). Consequently, a lesion without enhancement on gadolinium-enhanced MRI can easily be misinterpreted, potentially underestimating its malignant potential. Given the significant differences in the management of malignant and benign lesions, an accurate diagnosis is imperative for appropriate intervention. We present a case of PCNSTL without MRI enhancement. In instances of non-enhancing lesions with a clinical suspicion of malignancy, a more aggressive diagnostic approach should be adopted.
