Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 6, 2024; 12(19): 4003-4009
Published online Jul 6, 2024. doi: 10.12998/wjcc.v12.i19.4003
A rare presentation of unicentric Castleman's disease in the thigh: A case report and review of literature
Sultan AlSheikh, Abdulmajeed Altoijry, Husain Al-Mubarak, Ofays Dakkam Alsallum, Fadi Alakeel, Tariq Alanezi
Sultan AlSheikh, Abdulmajeed Altoijry, Husain Al-Mubarak, Ofays Dakkam Alsallum, Tariq Alanezi, Division of Vascular Surgery, Department of Surgery, College of Medicine, King Saud University, Riyadh 11322, Saudi Arabia
Ofays Dakkam Alsallum, Division of Vascular Surgery, Department of Surgery, King Khalid Hospital Najran, Najran 11321, Saudi Arabia
Fadi Alakeel, Department of Pathology, College of Medicine, King Saud University, Riyadh 11322, Saudi Arabia
Author contributions: AlSheikh S, Altoijry A and Al-Mubarak H designed the research study; Alanezi T completed the first draft of this manuscript and performed the experiments and data collection; Alsallum OD and Alanezi T was involved in data collection; Alakeel F provided pathological findings; AlSheikh S, Altoijry A, Al-Mubarak H, Alsallum OD, lakeel F and Alanezi T revised the manuscript. All authors have read and approved the final version of the manuscript.
Informed consent statement: Informed written consent was obtained from the patient for the publication of this report and any accompanying images. A copy of the written consent form is available for review by the editor-in-chief of this journal upon request.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tariq Alanezi, MD, Doctor, Division of Vascular Surgery, Department of Surgery, College of Medicine, King Saud University, Ash Shaikh Hasan Ibn Abdullah Al Ash Shaikh Road, Riyadh 11322, Saudi Arabia. alanezitariq@gmail.com
Received: March 6, 2024
Revised: May 8, 2024
Accepted: May 21, 2024
Published online: July 6, 2024
Processing time: 114 Days and 19.3 Hours
Core Tip

Core Tip: Castleman's disease (CD) is a rare disorder primarily affecting lymph nodes and associated tissues. Clinical characteristics and survival vary significantly among the three histological subtypes of CD. Diagnosis of CD primarily relies on histopathological examination, supported by imaging modalities such as computed tomography scan, magnetic resonance imaging, and ultrasound. Histopathological examination is crucial for diagnosing both unicentric-CD (UCD) and multicentric-CD, especially after ruling out other disorders, including infections, malignancies, and autoimmune conditions. Despite its rarity, CD presents a range of treatment options. However, studies consistently highlight surgical resection as the optimal treatment modality, particularly for UCD.