Editorial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 6, 2024; 12(19): 3665-3670
Published online Jul 6, 2024. doi: 10.12998/wjcc.v12.i19.3665
Intensive care unit-acquired weakness – preventive, and therapeutic aspects; future directions and special focus on lung transplantation
Thirugnanasambandan Sunder
Thirugnanasambandan Sunder, Department of Heart Lung Transplantation and Mechanical Circulatory Support, Apollo Hospitals, Chennai 600086, Tamil Nadu, India
Author contributions: Sunder T designed the overall concept, outline of the manuscript, the discussion and design of the manuscript; contributed to the writing, editing the manuscript, and review of literature; and has read and approved the final manuscript.
Conflict-of-interest statement: Dr. Sunder has nothing to disclose.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Thirugnanasambandan Sunder, FRCS, MBBS, MS, Academic Editor, Consultant Cardiac Surgeon, Director, Surgeon, Department of Heart Lung Transplantation and Mechanical Circulatory Support, Apollo Hospitals, Greams Lane Off Greams Road, Chennai 600086, Tamil Nadu, India. sunder64@gmail.com
Received: March 14, 2024
Revised: April 24, 2024
Accepted: May 11, 2024
Published online: July 6, 2024
Processing time: 106 Days and 15.1 Hours
Core Tip

Core Tip: Increasing number of patients are being treated in the intensive care units (ICUs) with good outcomes. However, the incidence of ICU acquired weakness (ICU-AW) is also on the rise and is a cause of significant mortality and morbidity. While certain risk factors and pathogenetic mechanisms for the development of this condition have been identified, there still exists significant lacunae in our understanding of the same. The use of artificial intelligence with artificial neural networks and machine learning techniques appears promising to provide vital information which can be used to prevent and treat ICU-AW. The impact of this condition on lung transplantation, in the setting of globally prevalent donor organ scarcity, is discussed.