Meta-Analysis
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 26, 2024; 12(18): 3515-3528
Published online Jun 26, 2024. doi: 10.12998/wjcc.v12.i18.3515
Comparative efficacy and safety of Chinese patent medicines of iron deficiency anemia during pregnancy: A network meta-analysis
Jia-Chen Zou, Xian-Ling Jia, Hai-Xia Wang, Ying-Jie Su, Jing-Yu Zhu
Jia-Chen Zou, Xian-Ling Jia, School of Chinese Medicine, Weifang Medical University, Weifang 261053, Shandong Province, China
Hai-Xia Wang, Ying-Jie Su, Jing-Yu Zhu, Traditional Chinese Medicine Department, Affiliated Hospital of Weifang Medical University, Weifang 261031, Shandong Province, China
Author contributions: Zou JC contributed to conceptualization, software, data curation, writing-Original draft preparation; Wang HX contributed to conceptualization, methodology; Jia XL contributed to reviewing, editing, data curation and validation; Su YJ contributed to visualization, investigation, funding acquisition; Zhu JY contributed to software, validation, writing- reviewing and editing.
Supported by Shandong Province Traditional Chinese Medicine Science and Technology Project, No. Q-2022126; and Weifang Municipal Health Commission Traditional Chinese Medicine Scientific Research Project, No. 014, 2022 (Category 3).
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hai-Xia Wang, PhD, Chief Doctor, Traditional Chinese Medicine Department, Affiliated Hospital of Weifang Medical University, No. 2428 Yuhe Road, Kuiwen District, Weifang 261031, Shandong Province, China. wsy852893@163.com
Received: March 4, 2024
Revised: April 25, 2024
Accepted: May 15, 2024
Published online: June 26, 2024
Processing time: 106 Days and 1.4 Hours
Core Tip

Core Tip: The network meta-analysis demonstrated that combining Chinese proprietary medicines with oral iron (OI) for the treatment of iron-deficiency anaemia in pregnancy significantly improved clinical effective rate, improved red blood cell indicators and iron metabolism indicators, and reduced adverse pregnancy outcomes and adverse events. Based on the available evidence, it is recommended that the combination of Shengxuening Tablets with OI improve clinical efficacy and other outcome indicators. Further high-quality randomised controlled trials are needed to reassess or confirm this finding.