Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 16, 2024; 12(17): 3061-3075
Published online Jun 16, 2024. doi: 10.12998/wjcc.v12.i17.3061
Renin-angiotensin system inhibitors prescriptions in Chinese hospitalized chronic kidney disease patients
Chun Zhang, Zhi-Yu Duan, Sa-Sa Nie, Zhou Zhang, Xin-Ru Guo, Chao-Yang Zhang, Jing Dong, Guang-Yan Cai
Chun Zhang, Zhi-Yu Duan, Sa-Sa Nie, Zhou Zhang, Chao-Yang Zhang, Guang-Yan Cai, Department of Nephrology, The First Medical Centre, Chinese PLA General Hospital, Beijing 100853, China
Xin-Ru Guo, School of Medicine, Nankai University, Tianjin 300071, China
Jing Dong, National Engineering Laboratory for Medical Big Data Application Technology, Chinese PLA General Hospital, Beijing 100853, China
Author contributions: Cai GY designed the study; Zhang C, Duan ZY, Nie SS, Zhang Z, Guo XR, Zhang CY, Dong J performed the data collection and analysed the data; and Zhang C wrote the manuscript. All authors reviewed the manuscript.
Institutional review board statement: This study was approved by Ethics Committee of Chinese PLA General Hospital, Approval No. S2023-566-01.
Informed consent statement: The informed consent was waived by the ethics committee of The First Medical Centre, Chinese PLA General Hospital.
Conflict-of-interest statement: All authors declare no conflict of interest.
Data sharing statement: Data should be obtained by contacting the corresponding author.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Guang-Yan Cai, PhD, Chief Physician, Department of Nephrology, The First Medical Centre, Chinese PLA General Hospital, No. 28 Fuxing Road, Haidian District, Beijing 100853, China. vinxiong66@163.com
Received: March 9, 2024
Revised: April 23, 2024
Accepted: April 29, 2024
Published online: June 16, 2024
Processing time: 87 Days and 4.5 Hours
Core Tip

Core Tip: This study examines the prescribing trends of renin-angiotensin system inhibitors (RASI) in hospitalized Chinese chronic kidney disease (CKD) patients from 2010 to 2019. Despite guidelines recommending RASI as first-line therapy, findings reveal a peak in prescriptions around 2015 and 2016, followed by a slight decline. Factors such as younger age, male gender, and non-acute conditions increased RASI prescription likelihood. The research highlights a need for improved adherence to clinical guidelines in RASI application to enhance CKD patient care outcomes.