Editorial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 16, 2024; 12(17): 2917-2920
Published online Jun 16, 2024. doi: 10.12998/wjcc.v12.i17.2917
Vascular endothelium, a promising target for effectively treating fulminant diquat intoxication?
Xiang-Ying Cen, Yi Chen, Yong-An Xu, Guang-Yao Zhong
Xiang-Ying Cen, Yi Chen, Department of Intensive Care Medicine, Key Laboratory for Prevention and Treatment of Critical Illness in Dongguan City, Binhaiwan Central Hospital of Dongguan, Dongguan 523903, Guangdong Province, China
Yong-An Xu, Department of Emergency Medicine, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang Province, China
Guang-Yao Zhong, Department of Critical Care Medicine, Dongguan Eastern Central Hospital, Dongguan 523576, Guangdong Province, China
Author contributions: Chen Y designed the report; Xu YA and Zhong GY collected the patient’s clinical data; Cen XY analyzed the data and wrote the paper.
Supported by High-Level Scientific Research Incubation Fund Project of Binhaiwan Central Hospital of Dongguan, No. 2024003; and Major Project of National-Zhejiang Provincial Administration of Traditional Chinese Medicine, No. GZY-ZJ-KJ-24030.
Conflict-of-interest statement: There is no conflict of interest in the submission of this manuscript, and the manuscript has been approved by all authors for publication.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yi Chen, MD, PhD, Doctor, Department of Intensive Care Medicine, Binhaiwan Central Hospital of Dongguan, No. 111 Humen Road, Humen Town, Dongguan 523900, Guangdong Province, China. chenyi_icu@163.com
Received: November 9, 2023
Revised: January 30, 2024
Accepted: May 14, 2024
Published online: June 16, 2024
Processing time: 208 Days and 2.2 Hours
Core Tip

Core Tip: Based on our team's extensive experience and accumulated evidence in treating fulminant diquat (DQ) intoxication, we believe that endothelial cell injury plays a crucial role in the organ damage caused by DQ poisoning. However, there is currently a lack of reports on the role of endothelial cell injury in the development of multiple organ dysfunction syndrome induced by fulminant DQ poisoning. Some studies have observed vascular endothelium injury after DQ poisoning, but vascular endothelial cell is not the main focus of these studies.