Managing adult-onset Still's disease in pregnancy: A case report

doi:10.12998/wjcc.v12.i16.2837

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Jun 6, 2024 (publication date) through Jun 29, 2024

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World Journal of Clinical Cases

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Report

World J Clin Cases. Jun 6, 2024; 12(16): 2837-2841
Published online Jun 6, 2024. doi: 10.12998/wjcc.v12.i16.2837

Managing adult-onset Still's disease in pregnancy: A case report

Ji-Hyoun Kang

Ji-Hyoun Kang, Division of Rheumatology, Department of Internal Medicine, Chonnam National University Medical School & Hospital, Gwangju 61469, South Korea

Author contributions: Kang JH designed the research study, performed the research, and analyzed the data and wrote the manuscript; Kang JH has read and approved the final manuscript.

Informed consent statement: This report was prepared with the written consent of the patient.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/

Corresponding author: Ji-Hyoun Kang, MD, PhD, Assistant Professor, Division of Rheumatology, Department of Internal Medicine, Chonnam National University Medical School & Hospital, 42 Jebong-ro, Dong-gu, Gwangju 61469, South Korea. romi918@naver.com

Received: December 13, 2023
Revised: March 7, 2024
Accepted: April 10, 2024
Published online: June 6, 2024
Processing time: 167 Days and 21.6 Hours

Core Tip

Core Tip: This case study explores the intricate challenges faced by a 29-year-old woman with adult-onset Still’s disease (AOSD) during pregnancy, resulting in the premature birth of an infant diagnosed with neonatal hemophagocytic lympho-histiocytosis. Pregnancy exacerbates the risks associated with AOSD, including heightened chances of fetal loss and preterm birth. The management of AOSD during pregnancy involves utilizing nonsteroidal anti-inflammatory drugs, glucocorticoids, and, in severe cases, immunosuppressive agents despite potential fetal risks such as low birth weight and preterm birth, highlighting the delicate balance required in addressing the complexities of AOSD during gestation.