Editorial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 16, 2024; 12(14): 2304-2307
Published online May 16, 2024. doi: 10.12998/wjcc.v12.i14.2304
Investigating causal links between gastroesophageal reflux disease and essential hypertension
Gowthami Sai Kogilathota Jagirdhar, Yatinder Bains, Salim Surani
Gowthami Sai Kogilathota Jagirdhar, Department of Medicine, Saint Francis Health Science Center, Newark, NJ 07107, United States
Yatinder Bains, Department of Gastroenterology, Saint Michaels Medical Center, Newark, NJ 07102, United States
Salim Surani, Department of Medicine and Pharmacology, Texas A&M University, College Station, TX 77843, United States
Author contributions: Surani S and Bains Y designed the overall concept and outline of the manuscript; Jagirdhar GSK and Bains Y contributed to the discussion and design of the manuscript; Jagirdhar GSK, Bains Y and Surani S contributed to the writing, editing the manuscript and review of literature.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Salim Surani, FASP, MD, FCCP, MHSc, Adjunct Professor, Department of Medicine and Pharmacology, Texas A&M University, 40 Bizzell Street, College Station, TX 77843, United States. srsurani@hotmail.com
Received: February 14, 2024
Revised: March 17, 2024
Accepted: April 3, 2024
Published online: May 16, 2024
Core Tip

Core Tip: The relationship between gastroesophageal reflux disease (GERD) and hypertension (HTN) is multifaceted, involving mechanisms such as autonomic dysfunction, nitric oxide levels, and medication effects. GERD treatment, including anti-reflux surgery, may improve HTN control, highlighting the clinical relevance of understanding this association. However, the complex interplay of comorbidities and medications warrants further investigation to elucidate causal pathways and optimize patient management strategies.