Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 6, 2024; 12(13): 2286-2292
Published online May 6, 2024. doi: 10.12998/wjcc.v12.i13.2286
Refractory autoimmune hemolytic anemia in a patient with systemic lupus erythematosus and ulcerative colitis: A case report
Dai-Xing Chen, Yue Wu, Sui-Feng Zhang, Xiao-Jun Yang
Dai-Xing Chen, Yue Wu, Sui-Feng Zhang, Xiao-Jun Yang, Department of Digestive System, Chongqing Traditional Chinese Medicine Hospital, Chongqing 400021, China
Author contributions: Chen DX and Wu Y contributed to writing and editing of the manuscript and to collecting the data; Zhang SF contributed to the data analysis; Yang XJ contributed to the conceptualization and supervision. All the authors have read and approved the final manuscript.
Informed consent statement: All participants in the study or their legal guardians provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao-Jun Yang, MD, PhD, Chief Doctor, Department of Digestive System, Chongqing Traditional Chinese Medicine Hospital, No. 6 Panxi 7 Branch Road, Jiangbei District, Chongqing 400021, China. yangxj88@126.com
Received: January 23, 2024
Peer-review started: January 23, 2024
First decision: January 31, 2024
Revised: February 6, 2024
Accepted: March 27, 2024
Article in press: March 27, 2024
Published online: May 6, 2024
Processing time: 92 Days and 20.7 Hours
Core Tip

Core Tip: The association between ulcerative colitis (UC) and systemic lupus erythematosus (SLE) is a rare phenomenon. We first diagnosed a patient with coexisting UC and SLE with refractory autoimmune hemolytic anemia. Combined with the analysis of the cases indexed in PubMed, plasma exchange (PE) has been reported as a promising strategy for treating refractory autoimmune hemolytic anemia. The patient was successfully treated and maintained stable conditions through PE and continuous treatment with cyclophosphamide and hydroxychloroquine. Therefore, personalized treatment is currently the best approach.