Therapeutic effect of Wendan Decoction combined with mosapride on gastroesophageal reflux disease after esophageal cancer surgery

doi:10.12998/wjcc.v12.i13.2194

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. May 6, 2024; 12(13): 2194-2200
Published online May 6, 2024. doi: 10.12998/wjcc.v12.i13.2194

Therapeutic effect of Wendan Decoction combined with mosapride on gastroesophageal reflux disease after esophageal cancer surgery

Yu-Jing Zhang, Shen-Ping Wu

Yu-Jing Zhang, Shen-Ping Wu, Department of Oncology, Beijing Integrated Traditional Chinese and Western Medicine Hospital, Beijing 100039, China

Author contributions: Zhang YJ and Wu SP proposed the concept of this study; Wu SP participated in the data collection; Zhang YJ and Wu SP wrote the initial draft; Wu SP contributed to the formal analysis; Zhang YJ conducted guiding research, methodology, and visualization of the manuscript; Both authors participated in this study, validated it, and jointly reviewed and edited the manuscript.

Institutional review board statement: This study has been reviewed and approved by the Ethics Committee of Beijing Integrated Traditional Chinese and Western Medicine Hospital

Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.

Conflict-of-interest statement: We declare that there is no disclosure of any conflict of interest.

Data sharing statement: No additional data are available.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Yu-Jing Zhang, MM, Attending Doctor, Department of Oncology, Beijing Integrated Traditional Chinese and Western Medicine Hospital, No. 3 East Street, Yongding Road, Haidian District, Beijing 100039, China. tzvz674@163.com

Received: January 25, 2024
Peer-review started: January 25, 2024
First decision: February 8, 2024
Revised: February 9, 2024
Accepted: March 27, 2024
Article in press: March 27, 2024
Published online: May 6, 2024

Core Tip

Core Tip: This study suggests that combining Wendan Decoction with mosapride is an effective and safe therapy for managing gastroesophageal reflux disease (GERD) after esophageal cancer surgery. It improves GERD symptoms, esophageal motility, gastric emptying, and the quality of life of patients. Larger studies with longer follow-up periods are needed to further validate these findings.