Parenteral iron therapy in children with iron deficiency anemia

doi:10.12998/wjcc.v12.i13.2138

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May 6, 2024 (publication date) through May 9, 2024

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. May 6, 2024; 12(13): 2138-2142
Published online May 6, 2024. doi: 10.12998/wjcc.v12.i13.2138

Parenteral iron therapy in children with iron deficiency anemia

Jelena Roganovic

Jelena Roganovic, Department of Pediatric Hematology and Oncology, Children’s Hospital Zagreb, 10000 Zagreb, Croatia

Jelena Roganovic, Faculty of Biotechnology and Drug Development, University of Rijeka, Rijeka 51000, Croatia

Author contributions: Roganovic J designed and wrote the article.

Conflict-of-interest statement: The author has nothing to disclose.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/

Corresponding author: Jelena Roganovic, MD, PhD, Adjunct Professor, Chief Doctor, Full Professor, Senior Researcher, Department of Pediatric Hematology and Oncology, Children’s Hospital Zagreb, Klaiceva 16, 10000 Zagreb, Croatia. roganovic.kbcri@gmail.com

Received: December 12, 2023
Revised: February 10, 2024
Accepted: April 7, 2024
Published online: May 6, 2024

Core Tip

Core Tip: Intravenous iron is an important but underutilized therapy in children with iron deficiency anemia (IDA) who fail to respond to oral iron. Considering IDA-related long-term negative neurobehavioral effects, it is important to switch to intravenous iron timely and safely. Over the last decades there has been a remarkable improvement in the quality of intravenous iron formulations with greater efficacy, tolerability, and safety.