Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 26, 2024; 12(12): 2079-2085
Published online Apr 26, 2024. doi: 10.12998/wjcc.v12.i12.2079
Overlapping infections of Mycobacterium canariasense and Nocardia farcinica in an immunocompetent patient: A case report
Hai-Yan Huang, Kun-Peng Bu, Jin-Wei Liu, Jing Wei
Hai-Yan Huang, Kun-Peng Bu, Jing Wei, Department of Comprehensive Internal Medicine, The Affiliated Cancer Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China
Jin-Wei Liu, Department of Doppler Ultrasound, The Second Nanning People's Hospital, Nanning 530021, Guangxi Zhuang Autonomous Region, China
Author contributions: Huang HY and Wei J substantial contribution to the conception and design of the work; Huang HY, Wei J, Bu KP and Liu JW contribution to the acquisition, analysis, interpretation of data for the work; Huang HY contribution to article writing and revising; Bu KP and Wei J agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. All authors have read and approve the final manuscript and contributed to the conception and design of the work.
Supported by The Guangxi TCM Suitable Technology Development and Promotion Project, No. GZSY20-20.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Jing Wei, Doctor, Department of Comprehensive Internal Medicine, The Affiliated Cancer Hospital of Guangxi Medical University, No. 71 Hedi Road, Nanning 530021, Guangxi Zhuang Autonomous Region, China.
Received: November 11, 2023
Revised: February 26, 2024
Accepted: April 2, 2024
Published online: April 26, 2024
Core Tip

Core Tip: Non-tuberculous mycobacteria (NTM) and Nocardia are opportunistic pathogens that can occur in immunocompromised patients who present with atypical clinical symptoms. Mycobacterium canariasense (M. canariasense) is a rare NTM species was first identified 20 years ago. We describe a patient with multiple lung nodules of unequal size with uneven internal density, and multiple small burrs at the edges of these lung lesions. The pathology results were inconsistent with malignancy, and metagenomic next-generation sequencing indicated overlapping infections of M. canariasense, Nocardia farcinica, and Candida parapsilosis. The anti-infective treatment was successful.