Clinical Trials Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 26, 2024; 12(12): 2050-2055
Published online Apr 26, 2024. doi: 10.12998/wjcc.v12.i12.2050
Transient elastography with controlled attenuation parameter for the diagnosis of colorectal polyps in patients with nonalcoholic fatty liver disease
Lan Wang, Yan-Fei Li, Li-Feng Dong
Lan Wang, Yan-Fei Li, Li-Feng Dong, Department of Gastroenterology, Beijing Chuiyangliu Hospital, Beijing 100022, China
Co-first authors: Lan Wang and Yan-Fei Li.
Author contributions: Wang L, Li YF and Dong LF designed the research; Wang L performed the research; Li YF contributed new analytic tools; Wang L and Li YF analyzed the data; Wang L wrote the paper; all authors have read and approved the final manuscript.
Supported by the Special Research Project of the Capital’s Health Development, No. 2024-3-7037; and the Beijing Clinical Key Specialty Project.
Institutional review board statement: The study was approved by the Human Ethics Committee of Beijing ChuiYangLiu Hospital (No. 2024-002KY).
Informed consent statement: The requirement for informed consent from patients was waived (No. 2024-002KY).
Conflict-of-interest statement: All the authors have read and agreed with the contents of the manuscript, and there are no conflicts of interest to disclose.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at
CONSORT 2010 statement: The authors have read the CONSORT 2010 statement, and the manuscript was prepared and revised according to the CONSORT 2010 statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Li-Feng Dong, MD, Doctor, Department of Gastroenterology, Beijing Chuiyangliu Hospital, No. 2 Chuiyangliu South Street, Chaoyang District, Beijing 100022, China.
Received: December 23, 2023
Peer-review started: December 23, 2023
First decision: February 24, 2024
Revised: March 7, 2024
Accepted: March 28, 2024
Article in press: March 28, 2024
Published online: April 26, 2024
Core Tip

Core Tip: This study was designed to explore the risk factors associated with colorectal polyps in patients with nonalcoholic fatty liver disease (NAFLD) by analyzing liver-controlled attenuation parameters (liver-CAPs) and establishing a diagnostic model. We found that the triglyceride (TG) and liver-CAPs in patients with colorectal polyps were significantly greater than those in patients without colorectal polyps. When the liver-CAP was greater than 291 dB/m, colorectal polyps were more likely to occur. Additionally, no difference was observed in the diagnostic efficacy or specificity between liver-CAP and TG+CAP. Liver-CAP alone can also be used to diagnose NAFLD patients with colorectal polyps.