Systematic Reviews
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 6, 2024; 12(1): 107-118
Published online Jan 6, 2024. doi: 10.12998/wjcc.v12.i1.107
Impact of frailty on outcomes of elderly patients undergoing percutaneous coronary intervention: A systematic review and meta-analysis
Shi-Shi Wang, Wang-Hao Liu
Shi-Shi Wang, Department of Emergency Medicine, Huzhou Third Municipal Hospital, The Affiliated Hospital of Huzhou University, Huzhou 313000, Zhejiang Province, China
Wang-Hao Liu, Department of Geriatrics, Huzhou Third Municipal Hospital, the Affiliated Hospital of Huzhou University, Huzhou 313000, Zhejiang Province, China
Author contributions: Wang SS and Liu WH designed the research; Wang SS and Liu WH performed the research; Wang SS analyzed the data; Wang SS and Liu WH wrote the paper.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wang-Hao Liu, MD, Professor, Research Scientist, Department of Geriatrics, Huzhou Third Municipal Hospital, the Affiliated Hospital of Huzhou University, No. 2088 Tiaoxi East Road, Wuxing District, Huzhou 313000, Zhejiang Province, China. liuwanghaodoctor@126.com
Received: October 27, 2023
Peer-review started: October 27, 2023
First decision: November 21, 2023
Revised: November 30, 2023
Accepted: December 15, 2023
Article in press: December 15, 2023
Published online: January 6, 2024
Core Tip

Core Tip: This comprehensive meta-analysis elucidates the significant impact of frailty on outcomes in elderly patients undergoing percutaneous coronary intervention (PCI). The study underscores the consistent association between frailty and heightened risks of in-hospital mortality, all-cause mortality, major adverse cardiovascular events, and major bleeding. The convergence of results across diverse study designs, patient populations, and methodological approaches underscores the robustness of these findings. Recognizing frailty as a potent predictor allows for tailored care plans, emphasizing the need for standardized frailty assessment in the pre-PCI evaluation of elderly patients.