Case Report
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Feb 26, 2023; 11(6): 1426-1433
Published online Feb 26, 2023. doi: 10.12998/wjcc.v11.i6.1426
Primary malignant melanoma of the esophagus: A case report
Qian-Qian Wang, Yan-Mei Li, Geng Qin, Fang Liu, Ying-Ying Xu
Qian-Qian Wang, Department of Gastroenterology, Peking University China-Japan Friendship School of Clinical Medicine, Beijing 100029, China
Yan-Mei Li, Geng Qin, Fang Liu, Ying-Ying Xu, Department of Gastroenterology, China-Japan Friendship Hospital, Beijing 100029, China
Author contributions: Wang QQ contributed to manuscript writing and editing; Li YM, Qin G and Liu F contributed to data collection; Xu YY contributed to conceptualization and supervision; all authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ying-Ying Xu, MD, Doctor, Department of Gastroenterology, China-Japan Friendship Hospital, No. 2 Yinghua East Road, Chaoyang District, Beijing 100029, China. 15901033816@163.com
Received: December 18, 2022
Peer-review started: December 18, 2022
First decision: January 3, 2023
Revised: January 7, 2023
Accepted: February 7, 2023
Article in press: February 7, 2023
Published online: February 26, 2023
Processing time: 68 Days and 4.2 Hours
Core Tip

Core Tip: We report a case of a 73-year-old male with primary malignant melanoma of the esophagus (PMME) and extensive systemic multiple metastases, with an unavoidable mortality outcome despite aggressive diagnosis and treatment. Through this case report and literature review, we aimed to further improve clinicians' understanding of the clinical and molecular pathological features, origin and pathogenesis of PMME, to avoid misdiagnosis and missed diagnoses, to present cutting-edge treatment advances and to develop individualized and comprehensive treatment plans tailored to patients in an effort to improve their clinical outcomes.