Case Report
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Feb 26, 2023; 11(6): 1341-1348
Published online Feb 26, 2023. doi: 10.12998/wjcc.v11.i6.1341
Functioning gonadotroph adenoma with hyperestrogenemia and ovarian hyperstimulation in a reproductive-aged woman: A case report and review of literature
Ying He, Yu-Tao Gao, Li Sun
Ying He, Yu-Tao Gao, Li Sun, Department of Gynecological Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen 518116, Guangdong Province, China
Li Sun, Department of Gynecological Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Author contributions: He Y contributed to manuscript writing, editing, and data collection; Gao YT contributed to manuscript editing; Sun L contributed to supervision; all authors have read and approved the final manuscript.
Supported by Shenzhen High-level Hospital Construction Fund and Sanming Project of Medicine in Shenzhen, No. SZSM201812075.
Informed consent statement: Written informed consent was obtained from the patient for the publication of any potentially identifiable images or data included in this article.
Conflict-of-interest statement: The authors have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Li Sun, MD, Chief Doctor, Department of Gynecological Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 17 Panjiayuan Nanli, Chaoyang District, Beijing 100021, China. xjsunli@sina.com
Received: November 26, 2022
Peer-review started: November 26, 2022
First decision: December 19, 2022
Revised: December 28, 2022
Accepted: February 2, 2023
Article in press: February 2, 2023
Published online: February 26, 2023
Processing time: 89 Days and 15.8 Hours
Core Tip

Core Tip: Functional gonadotroph adenomas (FGAs) are rare pituitary gland tumors. Here, we describe a case of FGAs in a woman of reproductive age with abdominal pain, irregular menstruation, hyperestrogenemia, and ovarian mass. We would like to share our experience of diagnosis and treatment, which will help clinicians make appropriate decisions in the future.