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World J Clin Cases. Feb 26, 2023; 11(6): 1261-1266
Published online Feb 26, 2023. doi: 10.12998/wjcc.v11.i6.1261
Clinical and pathophysiological understanding of the hepatorenal syndrome: Still wrong or still not exactly right?
Benjamin Wilde, Ali Canbay, Antonios Katsounas
Benjamin Wilde, Department of Nephrology, University of Duisburg-Essen, University Hospital Essen, Essen 45147, Germany
Ali Canbay, Antonios Katsounas, Department of Medicine, Ruhr University Bochum, Bochum 44892, Germany
Author contributions: Wilde B performed the majority of the writing and performed research of scientific literature; Canbay A prepared the figure and performed research of scientific literature; Katsounas A designed the outline, performed research of scientific literature, coordinated the writing and performed final editing.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Antonios Katsounas, MD, PhD, Deputy Director, Doctor, Professor, Department of Medicine, Ruhr University Bochum, Universitätsklinikum Knappschaftskrankenhaus Bochum GmbH In der Schornau 23-25, Bochum 44892, Germany. antonios.katsounas@kk-bochum.de
Received: October 16, 2022
Peer-review started: October 16, 2022
First decision: November 26, 2022
Revised: December 15, 2022
Accepted: February 3, 2023
Article in press: February 3, 2023
Published online: February 26, 2023
Processing time: 130 Days and 18.9 Hours
Core Tip

Core Tip: This minireview challenges simplified views of the hepatorenal syndrome in the context of diagnostics and therapy stressing the need for further evidence to advance the knowledge on this syndrome.