Copyright
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 16, 2023; 11(35): 8270-8275
Published online Dec 16, 2023. doi: 10.12998/wjcc.v11.i35.8270
Published online Dec 16, 2023. doi: 10.12998/wjcc.v11.i35.8270
Ratio of hemoglobin to mean corpuscular volume: A new index for discriminating between iron deficiency anemia and thalassemia trait
Qing-Chun Yao, Department of Oncology, Taizhou Fourth People's Hospital, Taizhou 225300, Jiangsu Province, China
Hui-Li Zhai, Hou-Cai Wang, Department of Hematology, Shanghai Tenth People's Hospital, Shanghai 200072, China
Author contributions: Yao QC performed the study and draft the manuscript; Zhai HL collected the data and drafted the manuscript; Wang HC designed the study and analyzed the data. All authors have read and approved the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Shanghai Tenth People’s Hospital Institutional Review Board (Approval No. 23K190).
Informed consent statement: All data analyzed in our study were retrospectively collected. No patient consent was necessary.
Conflict-of-interest statement: All the authors declare no conflict of interest.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at houcaiwang@163.com.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hou-Cai Wang, MD, Chief Doctor, Department of Hematology, Shanghai Tenth People’s Hospital, No. 301 Yanchang Road, Shanghai 200072, China.
Received: October 26, 2023
Peer-review started: October 26, 2023
First decision: November 20, 2023
Revised: December 1, 2023
Accepted: December 6, 2023
Article in press: December 6, 2023
Published online: December 16, 2023
Processing time: 48 Days and 21.9 Hours
Peer-review started: October 26, 2023
First decision: November 20, 2023
Revised: December 1, 2023
Accepted: December 6, 2023
Article in press: December 6, 2023
Published online: December 16, 2023
Processing time: 48 Days and 21.9 Hours
Core Tip
Core Tip: The ratio of hemoglobin to mean corpuscular volume was proposed and validated as a new index for discriminating between iron deficiency anemia and thalassemia trait, with a sensitivity and a specificity of 93.5% and 78.4%, respectively. This new index has good diagnostic performance and is useful in under-resourced scenarios.