Editorial
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 6, 2023; 11(34): 8094-8098
Published online Dec 6, 2023. doi: 10.12998/wjcc.v11.i34.8094
Advances and future directions in keloid research: Pathogenesis, diagnosis and personalized treatment strategies
Song-Yun Zhao, Dan Wu, Chao Cheng, Jia-Heng Xie
Song-Yun Zhao, Chao Cheng, Department of Neurosurgery, Wuxi People’s Hospital Affiliated to Nanjing Medical University, Wuxi 214000, Jiangsu Province, China
Dan Wu, Department of Dermatology, Huashan Hospital, Fudan University, Shanghai 200000, China
Jia-Heng Xie, Department of Plastic Surgery, Xiangya Hospital, Central South University, Changsha 410000, Hunan Province, China
Author contributions: Wu D and Cheng C performed the study; Zhao SY and Xie JH analyzed the data and wrote the manuscript; all authors read and approved the final manuscript.
Conflict-of-interest statement: The authors deny any conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jia-Heng Xie, PhD, Researcher, Department of Plastic Surgery, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Kaifu District, Changsha 410000, Hunan Province, China. xiejiaheng@csu.edu.cn
Received: October 11, 2023
Peer-review started: October 11, 2023
First decision: October 24, 2023
Revised: October 28, 2023
Accepted: November 10, 2023
Article in press: November 10, 2023
Published online: December 6, 2023
Core Tip

Core Tip: This article provides a comprehensive review of keloids, which are abnormal outcomes of wound healing. Keloids can lead to dysfunction and aesthetic deformities pathogenesis is influenced by genetic, environmental and immune responses. The evolution of keloid treatment has shifted from traditional surgical excision to modern therapies, including injections and radiation therapy. The article emphasizes the need for continued research to better understand keloid development and improve therapeutic strategies for this complex condition.