Case Report
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 16, 2023; 11(32): 7920-7925
Published online Nov 16, 2023. doi: 10.12998/wjcc.v11.i32.7920
Interstitial pneumonia combined with nocardia cyriacigeorgica infection: A case report
Dao-Da Qi, Yi Zhuang, Yang Chen, Jing-Jing Guo, Ze Zhang, Yan Gu
Dao-Da Qi, Yang Chen, Jing-Jing Guo, Ze Zhang, Yan Gu, Department of Geriatrics, The Second Hospital of Nanjing, Nanjing University of Chinese Medicine, Nanjing 210003, Jiangsu Province, China
Yi Zhuang, Department of Respiratory and Critical Care Medicine, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210006, Jiangsu Province, China
Author contributions: All authors examined the patient; Zhuang Y and Gu Y participated in the discussion for the treatment and gave important suggestions; Qi DD and Chen Y drafted the manuscript; All authors critically revised the paper for important intellectual content, and all authors approved the final version of the manuscript.
Supported by Medical Science and Technology Development Foundation, Nanjing Department of Health, No. YKK20067.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors declare no conflict of interest associated with this manuscript.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yan Gu, MD, Doctor, Department of Geriatrics, The Second Hospital of Nanjing, Nanjing University of Chinese Medicine, No. 1-1, Zhongfu Road, Gulou District, Jiangsu Province, Nanjing 210003, China. guyan703@foxmail.com
Received: September 26, 2023
Peer-review started: September 26, 2023
First decision: October 17, 2023
Revised: October 25, 2023
Accepted: November 2, 2023
Article in press: November 2, 2023
Published online: November 16, 2023
Processing time: 50 Days and 14.4 Hours
Core Tip

Core Tip: In patients with interstitial pneumonia receiving oral steroids and immunosuppressants, the presence of new nodules, masses, or cavitary lesions should raise suspicion of concurrent Nocardia infection. In addition to routine examinations and tests, metagenomic next-generation sequencing can provide rapid pathogen identification, facilitating early targeted antimicrobial therapy and ultimately improving patient outcomes.