Moawad MHE, Alkhawaldeh IM, Naswhan AJ. Efficacy of probiotics supplementation in amelioration of celiac disease symptoms and enhancement of immune system. World J Clin Cases 2023; 11(32): 7741-7744 [PMID: 38073702 DOI: 10.12998/wjcc.v11.i32.7741]
Corresponding Author of This Article
Abdulqadir J Naswhan, MSc, Research Scientist, Nursing Department, Hamad Medical Corporation, Rayyan Road, Doha 3050, Qatar. anashwan@hamad.qa
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Editorial
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Author contributions: Ibraheem M Alkhawaldeh, Mostafa Hossam-Eldin Moawad and Abdulqadir J Nashwan contributed to this paper; Ibraheem M Alkhawaldeh and Mostafa Hossam-Eldin Moawad designed the overall concept and outline of the manuscript; Ibraheem M Alkhawaldeh, Mostafa Hossam-Eldin Moawad, and Abdulqadir J Nashwan contributed to the writing, and editing the manuscript, illustrations, and review of the literature.
Conflict-of-interest statement: All the authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Abdulqadir J Naswhan, MSc, Research Scientist, Nursing Department, Hamad Medical Corporation, Rayyan Road, Doha 3050, Qatar. anashwan@hamad.qa
Received: October 1, 2023 Peer-review started: October 1, 2023 First decision: October 24, 2023 Revised: October 27, 2023 Accepted: November 9, 2023 Article in press: November 9, 2023 Published online: November 16, 2023 Processing time: 45 Days and 20.5 Hours
Core Tip
Core Tip: In the context of celiac disease (CD), probiotics emerge as a multifaceted therapeutic approach with promising implications. Clinical trials demonstrate their potential to modulate immune responses, alleviate gastrointestinal symptoms, and reshape the gut microbiota in CD patients. Notably, specific probiotic strains have shown the ability to enzymatically break down immunotoxic gluten peptides, addressing a central challenge in CD pathogenesis. This dual-pronged role positions probiotics as a holistic means of CD management, offering immunomodulation and symptom relief to patients while potentially mitigating the toxicity of gluten peptides. Probiotics thus represent an encouraging avenue for enhancing the quality of life for individuals living with CD, underscoring their significance in the evolving landscape of CD treatment.
