Case Report
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 6, 2023; 11(31): 7656-7662
Published online Nov 6, 2023. doi: 10.12998/wjcc.v11.i31.7656
Sneddon's syndrome concurrent with cerebral venous sinus thrombosis: A case report
Yue Heng, Yu-Feng Tang, Xian-Wen Zhang, Jing-Feng Duan, Jian Shi, Qian Luo
Yue Heng, Yu-Feng Tang, Xian-Wen Zhang, Jing-Feng Duan, Jian Shi, Qian Luo, Department of Neurology, Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Mianyang 621000, Sichuan Province, China
Author contributions: Heng Y, Luo Q, Tang YF, Zhang XW, Duan JF, and Shi J designed the research study; Heng Y and Luo Q analyzed the data and wrote the manuscript; all authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qian Luo, MD, Doctor, Department of Neurology, Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, No. 12 Changjia Lane, Fucheng District, Mianyang 621000, Sichuan Province, China. lqmych@163.com
Received: August 20, 2023
Peer-review started: August 20, 2023
First decision: October 10, 2023
Revised: October 13, 2023
Accepted: October 26, 2023
Article in press: October 26, 2023
Published online: November 6, 2023
Processing time: 78 Days and 1 Hours
Core Tip

Core Tip: A 26-year-old woman presented with recurrent episodes of paroxysmal unilateral limb weakness accompanied by skin mottling, seizures, and cognitive impairment. Digital subtraction angiography revealed cerebral venous sinus thrombosis (CVST). Despite negative antiphospholipid antibody results, skin biopsy indicated chronic inflammatory cell infiltration. The patient was treated using anticoagulation, antiepileptic therapy, and supportive care, which resulted in symptom improvement. The coexistence of Sneddon's syndrome (SS) and CVST is rare and the underlying pathophysiology remains uncertain. This case underscores the challenge in diagnosis and highlights the need for early clinical differentiation to facilitate accurate assessment and prompt intervention.