Randomized Controlled Trial
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 6, 2023; 11(31): 7619-7628
Published online Nov 6, 2023. doi: 10.12998/wjcc.v11.i31.7619
Protective effect of sevoflurane on lung function of elderly chronic obstructive pulmonary disease patients undergoing total hip arthroplasty
Yuan Yao, Man-Si Zhang, Yue-Bing Li, Ming-Zhe Zhang
Yuan Yao, Department of Anesthesiology, The Second Hospital of Jiaxing, Jiaxing 314000, Zhejiang Province, China
Man-Si Zhang, Department of Pharmacy, Shangrao Municipal Hospital, Shangrao 334000, Jiangxi Province, China
Yue-Bing Li, Department of Anesthesiology, The Second Affiliated Hospital of Zhejiang University of Traditional Chinese Medicine, Hangzhou 310005, Zhejiang Province, China
Ming-Zhe Zhang, Department of Anesthesiology, Dingzhou People’s Hospital, Dingzhou 073000, Hebei Province, China
Author contributions: Yao Y and Zhang MZ proposed the concept of this study; Yao Y and Li YB have made contributions to data collection; Yao Y and Zhang MS contributed to formal analysis; Yao Y, Zhang MS, and Zhang MZ participated in the survey; Yao Y has contributed to these methods and prepared the first draft; Li YB and Zhang MZ guided the research; Yao Y validated this study; Zhang MZ and Li YB contributed to the visualization of this study; Yao Y, Zhang MZ, Li YB, and Zhang MS jointly reviewed and edited the manuscript.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Committee of Jiaxing Second Hospital.
Clinical trial registration statement: This study was registered in February 2018. Registration identification number is ChiCTR1900021234.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
CONSORT 2010 statement: The authors have read the CONSORT 2010 statement, and the manuscript was prepared and revised according to the CONSORT 2010 statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ming-Zhe Zhang, MSc, Attending Doctor, Department of Anesthesiology, Dingzhou People’s Hospital, Jianshe Street, Dingzhou 073000, Hebei Province, China. 15194968994@163.com
Received: September 19, 2023
Peer-review started: September 19, 2023
First decision: October 8, 2023
Revised: October 10, 2023
Accepted: October 23, 2023
Article in press: October 23, 2023
Published online: November 6, 2023
Processing time: 48 Days and 0.9 Hours
Core Tip

Core Tip: Sevoflurane exhibits a protective effect on lung function in elderly chronic obstructive pulmonary disease patients undergoing total hip arthroplasty. It reduces the incidence of postoperative pulmonary complications, improves lung function parameters, and decreases inflammatory and oxidative stress markers. Additionally, it alleviates postoperative pain. These findings highlight the potential benefits of using sevoflurane as an anesthesia choice for this patient population.