Case Report
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Oct 26, 2023; 11(30): 7469-7474
Published online Oct 26, 2023. doi: 10.12998/wjcc.v11.i30.7469
Hemodynamic instability following intravenous dexmedetomidine infusion for sedation under brachial plexus block: Two case reports
Ye Sull Kim, Chanhong Lee, Jeongmin Oh, Seonhwa Nam, A Ram Doo
Ye Sull Kim, Chanhong Lee, Jeongmin Oh, Seonhwa Nam, Department of Anesthesiology and Pain Medicine, Jeonbuk National University Hospital, Jeonju 54907, South Korea
A Ram Doo, Department of Anesthesiology and Pain Medicine, Jeonbuk National University Medical School and Hospital, Jeonju 54907, South Korea
A Ram Doo, Department of Anesthesiology and Pain Medicine, Research Institute of Clinical Medicine-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju 54907, South Korea
Author contributions: Kim YS contributed to manuscript writing and editing; Lee C contributed to investigation and data analysis; Oh J and Nam S contributed to data collection; Doo AR contributed to conceptualization and supervision; and all authors have read and approved the final manuscript.
Supported by the Fund of Biomedical Research Institute, Jeonbuk National University Hospital, Jeonju, Republic of Korea.
Informed consent statement: Written informed consent was obtained from the patients for publication of this case report.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: A Ram Doo, MD, PhD, Assistant Professor, Department of Anesthesiology and Pain Medicine, Jeonbuk National University Medical School and Hospital, 20 Geonji-ro, Deokjin-gu, Jeonju 54907, South Korea. ruiwin3518@gmail.com
Received: August 3, 2023
Peer-review started: August 3, 2023
First decision: September 4, 2023
Revised: September 13, 2023
Accepted: September 28, 2023
Article in press: September 28, 2023
Published online: October 26, 2023
Processing time: 83 Days and 3.5 Hours
Core Tip

Core Tip: Although severe, there are few reports of complications with dexmedetomidine (DMED) administration following brachial plexus block. Profound bradycardia can occur even in healthy individuals with DMED administration following brachial plexus block. It can trigger refractory hypotension without apparent bradycardia in patients with decreased cardiac function. Therefore, clinicians must be aware of these potential yet critical consequences while selecting sedatives.