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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 26, 2023; 11(3): 635-644
Published online Jan 26, 2023. doi: 10.12998/wjcc.v11.i3.635
Published online Jan 26, 2023. doi: 10.12998/wjcc.v11.i3.635
Rescuing “hopeless” avulsed teeth using autologous platelet-rich fibrin following delayed reimplantation: Two case reports
Yang Yang, Yan-Li Liu, Lie-Ni Jia, Jun-Jun Wang, Min Zhang, State Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases & Shaanxi International Joint Research Center for Oral Diseases, Department of General Dentistry and Emergency, School of Stomatology, Fourth Military Medical University, Xi'an 710032, Shaanxi Province, China
Author contributions: Yang Y, Jia LN and Wang JJ performed the dental treatment; Yang Y and Liu YL reviewed the literature and contributed to the drafting of the manuscript; Zhang M checked all aspects of this paper, including data collection, data analysis and paper writing; All authors have read and approved the final manuscript.
Supported by Natural Science Foundation of China , No. 31971248 ; and National Clinical Research Center for Oral Diseases Project of Military Stomatology , No. LCA202007 .
Informed consent statement: Informed written consent was obtained from the patients for publication of this report and any accompanying images.
Conflict-of-interest statement: All authors report having no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read CARE Checklist (2016), and the manuscript was prepared and revised according to CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Min Zhang, MD, PhD, Professor, State Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases, Department of General Dentistry and Emergency, School of Stomatology, Fourth Military Medical University, No. 145 Changle West Road, Xincheng District, Xi'an 710032, Shaanxi Province, China.
Received: August 25, 2022
Peer-review started: August 25, 2022
First decision: November 22, 2022
Revised: December 10, 2022
Accepted: January 9, 2023
Article in press: January 9, 2023
Published online: January 26, 2023
Processing time: 144 Days and 1.2 Hours
Peer-review started: August 25, 2022
First decision: November 22, 2022
Revised: December 10, 2022
Accepted: January 9, 2023
Article in press: January 9, 2023
Published online: January 26, 2023
Processing time: 144 Days and 1.2 Hours
Core Tip
Core Tip: Tooth avulsion is one of the most severe types of dental trauma. Most avulsed teeth will undergo ankylosis and replacement resorption after delayed reimplantation and generally experience a poor prognosis. We previously demonstrated that autologous platelet-rich fibrin (PRF) could effectively help to control the occurrence and development of initial root resorption. In this report, we presented two clinical cases of avulsed teeth with delayed reimplantation that were treated with autologous PRF. Ideal periodontal healing over 12 mo of follow-up suggested that PRF, as an adjuvant therapy, may provide new insights and perspectives on the management of traditionally hopeless avulsed teeth.