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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Oct 16, 2023; 11(29): 7101-7106
Published online Oct 16, 2023. doi: 10.12998/wjcc.v11.i29.7101
Published online Oct 16, 2023. doi: 10.12998/wjcc.v11.i29.7101
Varicella-zoster virus meningitis with hypoglycorrhachia: A case report
Li-Juan Cao, Yi-Ming Zheng, Fan Li, Hong-Jun Hao, Feng Gao, Department of Neurology, Peking University First Hospital, Beijing 100034, China
Li-Juan Cao, Department Acupuncture and Moxibustion, Huguosi Traditional Chinese Medicine Hospital Attached to Beijing Traditional Chinese Medicine University, Beijing 100034, China
Author contributions: Cao LJ and Zheng YM contributed to the drafting, and reporting of the case; Li F and Hao HJ contributed to revision of the manuscript; Gao F contributed to the concept and revision of the manuscript; and all authors read and approved the final manuscript, and met the authorship criteria from the International Committee of Medical Journal Editors; Zheng YM and Gao F are the co-corresponding authors of this manuscript.
Informed consent statement: Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor of this journal.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yi-Ming Zheng, MD, Doctor, Department of Neurology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing 100034, China.
Received: May 15, 2023
Peer-review started: May 15, 2023
First decision: July 3, 2023
Revised: July 16, 2023
Accepted: August 3, 2023
Article in press: August 3, 2023
Published online: October 16, 2023
Processing time: 151 Days and 7.2 Hours
Peer-review started: May 15, 2023
First decision: July 3, 2023
Revised: July 16, 2023
Accepted: August 3, 2023
Article in press: August 3, 2023
Published online: October 16, 2023
Processing time: 151 Days and 7.2 Hours
Core Tip
Core Tip: We report a case of an immunocompetent 39-year-old male, presenting with severe headache and fevers, found to have varicella-zoster virus (VZV) meningitis by the metagenomic next-generation sequencing of cerebrospinal fluid. The cerebrospinal fluid analysis revealed hypoglycorrhachia. Our literature review identified only ten cases diagnosed with VZV meningitis with hypoglycorrhachia previously reported whose cerebrospinal fluid glucose was from 1.6 to 2.7 mmol/L. Although rare, the cerebrospinal fluid of patients with VZV meningitis may have hypoglycorrhachia, which broadens the understanding of the disease.