Retrospective Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 16, 2023; 11(26): 6051-6065
Published online Sep 16, 2023. doi: 10.12998/wjcc.v11.i26.6051
Predictive value of preoperative albumin-bilirubin score and other risk factors for short-term outcomes after open pancreatoduodenectomy
Hana Zavrtanik, Davide Cosola, David Badovinac, Benjamin Hadžialjević, Gašper Horvat, Danaja Plevel, Selene Bogoni, Paola Tarchi, Nicolò de Manzini, Aleš Tomažič
Hana Zavrtanik, David Badovinac, Benjamin Hadžialjević, Gašper Horvat, Danaja Plevel, Aleš Tomažič, Department of Abdominal Surgery, University Medical Centre Ljubljana, Ljubljana 1000, Slovenia
Davide Cosola, Selene Bogoni, Paola Tarchi, Nicolò de Manzini, Clinica Chirurgica, Azienda Sanitaria Universitaria Giuliano Isontina, Cattinara Hospital, Trieste 34149, Italy
Nicolò de Manzini, Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste 34149, Italy
Aleš Tomažič, Faculty of Medicine, University of Ljubljana, Ljubljana 1000, Slovenia
Author contributions: Zavrtanik H gave substantial contributions to the conception and design of the manuscript; Zavrtanik H, Cosola D, Badovinac D, Hadžialjević B, Horvat G, Plevel D, Bogoni S, and Tarchi P contributed to the acquisition, analysis, and interpretation of the data; all authors participated in drafting the manuscript; Tomažič A and de Manzini N critically revised the manuscript for important intellectual content.
Institutional review board statement: Based on local policies, retrospective reviews of existing medical records recorded by the investigator in an anonymous manner are exempt from Institutional Review Board review and do not require its approval.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare no conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Aleš Tomažič, MD, PhD, Chief Doctor, Professor, Surgeon, Department of Abdominal Surgery, University Medical Centre Ljubljana, 7 Zaloška Cesta, Ljubljana 1000, Slovenia. ales.tomazic@kclj.si
Received: April 27, 2023
Peer-review started: April 27, 2023
First decision: July 6, 2023
Revised: July 25, 2023
Accepted: August 7, 2023
Article in press: August 7, 2023
Published online: September 16, 2023
Processing time: 133 Days and 22 Hours
Core Tip

Core Tip: Pancreatoduodenectomy remains a challenging procedure with substantial potential for morbidity and mortality. Prognostic tools to preoperatively identify patients at high risk for postoperative complications could help tailor their perioperative management and optimize treatment outcomes. Due to its objectivity and simplicity being based on routine laboratory parameters, the albumin-bilirubin score can readily be implicated in clinical routine. We evaluated the clinical significance of preoperative albumin-bilirubin score in patients undergoing pancreatoduodenectomy in relation to short-term postoperative outcomes, namely, postoperative complications, pancreatic fistula, reoperation, and mortality. Additionally, other potential risk factors were assessed as well. In case of their recognition, the operating surgeon may opt for alternative management options to avoid unfavourable postoperative outcomes.