Qing Q, Zha P, Dai LY, Wang Y. Effect of different ventilation methods combined with pulmonary surfactant on neonatal acute respiratory distress syndrome. World J Clin Cases 2023; 11(25): 5878-5886 [PMID: 37727476 DOI: 10.12998/wjcc.v11.i25.5878]
Corresponding Author of This Article
Yang Wang, Doctor, Professor, Department of Pediatrics, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Shushan District, Hefei 230001, Anhui Province, China. yangwang202302@163.com
Research Domain of This Article
Pediatrics
Article-Type of This Article
Retrospective Cohort Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Sep 6, 2023; 11(25): 5878-5886 Published online Sep 6, 2023. doi: 10.12998/wjcc.v11.i25.5878
Effect of different ventilation methods combined with pulmonary surfactant on neonatal acute respiratory distress syndrome
Qing Qing, Ping Zha, Li-Ying Dai, Yang Wang
Qing Qing, Yang Wang, Department of Pediatrics, The First Affiliated Hospital of Anhui Medical University, Hefei 230001, Anhui Province, China
Ping Zha, Li-Ying Dai, Department of Neonatology, Anhui Provincial Children's Hospital, Hefei 230001, Anhui Province, China
Author contributions: Qing Q and Wang Y contributed to conception and design, provision of study materials or patients; Wang Y contributed to administrative support; All authors contributed to collection and assembly of data; Qing Q contributed to data analysis and interpretation, manuscript writing; All authors contributed to final approval of manuscript.
Institutional review board statement: The ethical audit certificate of this study was provided by the Ethics Committee of the First Affiliated Hospital of Anhui Medical University. (NO. AHYKD-LLWYH-036).
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: All the Authors have no conflict of interest related to the manuscript.
Data sharing statement: The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.
STROBE statement: The authors have read the STROBE Statement – checklist of items, and the manuscript was prepared and revised according to the STROBE Statement – checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yang Wang, Doctor, Professor, Department of Pediatrics, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Shushan District, Hefei 230001, Anhui Province, China. yangwang202302@163.com
Received: July 12, 2023 Peer-review started: July 12, 2023 First decision: August 2, 2023 Revised: August 7, 2023 Accepted: August 11, 2023 Article in press: August 11, 2023 Published online: September 6, 2023 Processing time: 51 Days and 5.4 Hours
Core Tip
Core Tip: We observed 20 children with respiratory distress syndrome who received different ventilation strategies combined with pulmonary surfactant (PS) therapy, we divided into two groups: The observation group received high-frequency oscillatory ventilation (HFOV) combined with PS, and the control group received controlled mechanical ventilation or synchronous intermittent mandatory ventilation combined with PS. The observed indicators included blood gas analysis pH value partial pressures of oxygen and carbon dioxide. Our research results showed that the integration of HFOV combine with PS has proven to effectively expedite the treatment duration, decrease the occurrence of complications, and secure the therapeutic efficacy in managing neonatal respiratory distress syndrome.
