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World J Clin Cases. Sep 6, 2023; 11(25): 5857-5862
Published online Sep 6, 2023. doi: 10.12998/wjcc.v11.i25.5857
Progress in the study and treatment of peri-device leak after left atrial appendage closure
Ying-Bo Qi, Hui-Min Chu
Ying-Bo Qi, Department of Cardiology, Health Science Center, Ningbo University, Ningbo 315000, Zhejiang Province, China
Hui-Min Chu, Department of Cardiology, Arrhythmia Center, Ningbo First Hospital, Ningbo 3153000, Zhejiang Province, China
Author contributions: Qi YB reviewed the literature and contributed to the manuscript drafting; Chu HM reviewed the manuscript; All authors issued approval of the final version.
Supported by Zhejiang Provincial Foundation for Medical and Health Sciences, No. 2021KY980.
Conflict-of-interest statement: All authors declare having no potential conflicts of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hui-Min Chu, MD, Professor, Department of Cardiology, Arrhythmia Center, Ningbo First Hospital, No. 59 Liuting Street, Ningbo 3153000, Zhejiang Province, China. epnbheart@163.com
Received: February 18, 2023
Peer-review started: February 18, 2023
First decision: May 8, 2023
Revised: May 28, 2023
Accepted: August 9, 2023
Article in press: August 9, 2023
Published online: September 6, 2023
Processing time: 194 Days and 15.8 Hours
Core Tip

Core Tip: For patients with atrial fibrillation with an increased risk of stroke and contraindications to long-term anticoagulation, percutaneous left atrial appendage closure has become an important alternative to long-term oral anticoagulation. Incomplete closure of the left atrial appendage closure during the procedure leads to faster blood flow in the interstitial space around the device, resulting in peri-device leak. The incidence, long-term safety, and management of peri-device leak are still inconclusive.