Case Report
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 26, 2023; 11(24): 5749-5754
Published online Aug 26, 2023. doi: 10.12998/wjcc.v11.i24.5749
Neonatal erythema multiforme associated with a rotavirus infection: A case report
Jung Jae Kim, Joon Kee Lee
Jung Jae Kim, Joon Kee Lee, Department of Pediatrics, Chungbuk National University Hospital, Cheongju 28644, South Korea
Joon Kee Lee, Department of Pediatrics, Chungbuk National University, Cheongju 28644, South Korea
Author contributions: Kim JJ and Lee JK were the patient’s attending physicians; Kim JJ reviewed the literature and contributed to manuscript drafting; Kim JJ and Lee JK were responsible for the revision of the manuscript; all authors issued final approval for the version to be submitted.
Informed consent statement: Written informed consent was obtained from the patient’s parents for publication of any accompanying images in the case report.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Joon Kee Lee, MD, PhD, Assistant Professor, Department of Pediatrics, Chungbuk National University Hospital, 776 1-Sunhwan-ro, Seowon-gu, Cheongju 28644, South Korea. leejoonkee@chungbuk.ac.kr
Received: April 17, 2023
Peer-review started: April 17, 2023
First decision: July 17, 2023
Revised: July 21, 2023
Accepted: August 2, 2023
Article in press: August 2, 2023
Published online: August 26, 2023
Core Tip

Core Tip: Various etiologies, including infections, medications, malignancy, and immunization, are responsible for erythema multiforme (EM). EM is extremely rare in the neonatal period. Some potential causes have been reported in the literature, including hepatitis B vaccination and certain infections. As demonstrated in the current case, rotavirus, which is a common pathogenic gastrointestinal virus in the neonatal period that is preventable via vaccination, could be a cause of EM. Physicians should make their best effort in scrutinizing the etiology of the illness.