Case Report
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 16, 2023; 11(23): 5580-5588
Published online Aug 16, 2023. doi: 10.12998/wjcc.v11.i23.5580
Anti-melanoma differentiation-associated gene 5 and anti-Ro52 antibody-dual positive dermatomyositis accompanied by rapidly lung disease: Three case reports
Wen-Zheng Ye, Shan-Shan Peng, You-Hong Hu, Mu-Ping Fang, Yu Xiao
Wen-Zheng Ye, You-Hong Hu, Mu-Ping Fang, Yu Xiao, Department of Dermatology, The Central Hospital of Xiaogan, Xiaogan Hospital Affiliated to Wuhan University of Science and Technology, Xiaogan 432000, Hubei Province, China
Shan-Shan Peng, Department of Respiratory and Critical Care Medicine, The Central Hospital of Xiaogan, Xiaogan Hospital Affiliated to Wuhan University of Science and Technology, Xiaogan 432000, Hubei Province, China
Author contributions: Xiao Y and Peng SS contributed to manuscript writing and editing, and data collection; Ye WZ, Xiao Y and Hu YH contributed to data analysis; Xiao Y and Fang MP contributed to conceptualization and supervision; All authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient and her parents for the publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yu Xiao, MD, Academic Research, Doctor, Department of Dermatology, The Central Hospital of Xiaogan, Xiaogan Hospital Affiliated to Wuhan University of Science and Technology, No. 6 People's Square, Xiaonan District, Xiaogan 432000, Hubei Province, China. yyyxy09@163.com
Received: May 9, 2023
Peer-review started: May 9, 2023
First decision: June 13, 2023
Revised: June 22, 2023
Accepted: July 18, 2023
Article in press: July 18, 2023
Published online: August 16, 2023
Core Tip

Core Tip: In this study, we presented three rare cases of anti-melanoma differentiation-associated gene 5 (Anti-MDA5) and anti-Ro52 dual positive clinically amyopathic dermatomyositis (DM) accompanied by rapidly interstitial lung disease (ILD). Moreover, we reviewed the clinical manifesetations, pathogenesis and therapy about it. More imterestingly, there was a similarity between anti-MDA5 associated DM complicated rapidly progressive ILD and severe coronavirus disease 2019 pneumomia.