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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 6, 2023; 11(22): 5204-5214
Published online Aug 6, 2023. doi: 10.12998/wjcc.v11.i22.5204
Published online Aug 6, 2023. doi: 10.12998/wjcc.v11.i22.5204
Combining the age-male-albumin-bilirubin-platelets score and shear wave elastography stratifies carcinogenic risk in hepatitis C patients after viral clearance
Rion Masaoka, Yoshinori Gyotoku, Ryosaku Shirahashi, Toshikuni Suda, Masaya Tamano, Department of Gastroenterology, Dokkyo Medical University Saitama Medical Center, Koshigaya 343-8555, Saitama, Japan
Author contributions: Masaoka R, Gyotoku Y, and Shirahashi R conceptualized and designed the study, collected data, carried out the initial analysis, and drafted the initial manuscript; Suda T and Tamano M coordinated and supervised data collection and critically reviewed the manuscript for important intellectual content; All the authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work.
Institutional review board statement: This study was approved by the ethics committee of the Dokkyo Medical University Saitama Medical Center (Approval No. 22105).
Informed consent statement: Patients were not required to give informed consent for the study because the analysis used anonymous clinical data that were obtained after each patient gave informed consent to treatment. For full disclosure, the details of this retrospective, observational study were published on the home page of the medical center.
Conflict-of-interest statement: Rion Masaoka, Yoshinori Gyotoku, Ryosaku Shirahasi, Toshikuni Suda, and MasayaTamano have no financial relationships relevant of this article to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Masaya Tamano, PhD, Professor, Department of Gastroenterology, Dokkyo Medical University Saitama Medical Center, 2-1-50 Minami-koshigaya, Koshigaya 343-8555, Saitama, Japan. mstamano@dokkyomed.ac.jp
Received: May 10, 2023
Peer-review started: May 10, 2023
First decision: June 20, 2023
Revised: June 23, 2023
Accepted: July 7, 2023
Article in press: July 7, 2023
Published online: August 6, 2023
Processing time: 85 Days and 4.6 Hours
Peer-review started: May 10, 2023
First decision: June 20, 2023
Revised: June 23, 2023
Accepted: July 7, 2023
Article in press: July 7, 2023
Published online: August 6, 2023
Processing time: 85 Days and 4.6 Hours
Core Tip
Core Tip: Predicting the risk of carcinogenesis is important in hepatitis C patients who achieve sustained virological response (SVR) following direct-acting antiviral therapy. Both the age-male-albumin-bilirubin-platelets (aMAP) score and the velocity of shear waves (Vs) measured by SWE have been shown to be useful for stratifying the risk of hepatocellular carcinoma (HCC) in such patients. This study demonstrated that, for hepatitis C patients after SVR at medium and high risk for HCC, combining the aMAP score and Vs to stratify the risk of carcinogenesis is more efficient than uniform surveillance of all patients.