Case Report
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 16, 2023; 11(17): 4152-4158
Published online Jun 16, 2023. doi: 10.12998/wjcc.v11.i17.4152
Glucocorticoid pulse therapy in an elderly patient with post-COVID-19 organizing pneumonia: A case report
Shinhee Park, Youngeun Jang, So-My Koo, Bo Da Nam, Hee-Young Yoon
Shinhee Park, Division of Allergy and Pulmonary Medicine, Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Bucheon 14584, South Korea
Youngeun Jang, So-My Koo, Hee-Young Yoon, Division of Allergy and Respiratory Diseases, Department of Internal Medicine, Soonchunhyang University Seoul Hospital, Seoul 04401, South Korea
Bo Da Nam, Department of Radiology, Soonchunhyang University Seoul Hospital, Seoul 04401, South Korea
Author contributions: Yoon HY designed research; Park S, Jang Y, Koo S-M, Nam BD, and Yoon H-Y performed research; Yoon H-Y and Park S wrote the paper; all the authors discussed the results and reviewed the manuscript.
Informed consent statement: Written informed consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hee-Young Yoon, MD, PhD, Assistant Professor, Division of Allergy and Respiratory Diseases, Department of Internal Medicine, Soonchunhyang University Seoul Hospital, 59, Daesagwan-ro, Yongsan-gu, Seoul 04401, South Korea. yhyoung85@schmc.ac.kr
Received: March 22, 2023
Peer-review started: March 22, 2023
First decision: April 28, 2023
Revised: April 29, 2023
Accepted: May 16, 2023
Article in press: May 16, 2023
Published online: June 16, 2023
Processing time: 82 Days and 7.3 Hours
Core Tip

Core Tip: In cases wherein standard glucocorticoid therapy is ineffective in patients with coronavirus disease 2019 (COVID-19) sequelae, glucocorticoid pulse therapy may be considered. This treatment approach was effective in the present case of an 81-year-old man with post-COVID-19 organizing pneumonia who developed acute respiratory failure after infection. The patient showed significant improvement in oxygen demand and imaging tests after three days of pulse treatment; he eventually recovered without any symptoms of interstitial lung disease. Therefore, glucocorticoid pulse therapy is a potential treatment option for patients with COVID-19 sequelae who require oxygen therapy and do not respond to standard therapy.