Copyright
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 6, 2023; 11(16): 3830-3836
Published online Jun 6, 2023. doi: 10.12998/wjcc.v11.i16.3830
Published online Jun 6, 2023. doi: 10.12998/wjcc.v11.i16.3830
Prevotella oris-caused meningitis and spinal canal infection: A case report
Wei-Wei Zhang, Chao Ai, Chien-Tai Mao, Department of Clinical Pharmacy, Beijing Tsinghua Changgung Hospital, School of Medicine, Tsinghua University, Beijing 102218, China
Dong-Kang Liu, Yi Guo, Department of Neurosurgery, Beijing Tsinghua Changgung Hospital, School of Medicine, Tsinghua University, Beijing 102218, China
Author contributions: Zhang WW contributed to manuscript writing and editing; Ai C, Liu DK and Mao CT contributed to data collection and analysis; Guo Y contributed to conceptualization and supervision; All authors read and approved the final manuscript.
Informed consent statement: The patient’s legal guardian provided informed written consent to publish this case report and any accompanying images.
Conflict-of-interest statement: All authors report no having relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yi Guo, MD, Doctor, Department of Neurosurgery, Beijing Tsinghua Changgung Hospital, School of Medicine, Tsinghua University, No. 168 Litang Road, Changping District, Beijing 102218, China. gya01246@btch.edu.cn
Received: January 7, 2023
Peer-review started: January 7, 2023
First decision: March 10, 2023
Revised: March 16, 2023
Accepted: April 12, 2023
Article in press: April 12, 2023
Published online: June 6, 2023
Peer-review started: January 7, 2023
First decision: March 10, 2023
Revised: March 16, 2023
Accepted: April 12, 2023
Article in press: April 12, 2023
Published online: June 6, 2023
Core Tip
Core Tip:Prevotella oris is an anaerobic, Gram-negative, nonpigmented bacterium that rarely results in central nervous system infection. To date, only 1 case has been reported of Prevotella oris causing central nervous system infection. We report a patient who suffered from meningitis and spinal canal infection due to Prevotella oris. Metagenomic next-generation sequencing identified the pathogen, although the cerebrospinal fluid and blood cultures were negative. Early detection of pathogens is crucial for patient survival and prognosis. We analyzed the characteristics of Prevotella oris-induced infection and found that all patients were male; the most commonly used antimicrobial agent was metronidazole.