Retrospective Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 26, 2023; 11(12): 2694-2707
Published online Apr 26, 2023. doi: 10.12998/wjcc.v11.i12.2694
Surgical management of pituitary adenoma during pregnancy
Xin-Yu Jia, Xiao-Peng Guo, Yong Yao, Kan Deng, Wei Lian, Bing Xing
Xin-Yu Jia, Department of Plastic Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100144, China
Xin-Yu Jia, Xiao-Peng Guo, Yong Yao, Kan Deng, Wei Lian, Bing Xing, Department of Neurosurgery, Key Laboratory of Endocrinology of Ministry of Health, China Pituitary Adenoma Specialist Council, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing 100730, China
Xin-Yu Jia, Department of Plastic Surgery, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
Xiao-Peng Guo, Yong Yao, Kan Deng, Wei Lian, Bing Xing, Department of Neurosurgery, Medical Research Center, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing 100730, China
Author contributions: All authors contributed to the study conception and design; Jia XY, Guo XP, Yao Y, Deng K, Lian W and Xing B contributed to material preparation, data collection and analysis; Jia XY wrote the first draft of the manuscript; all authors contributed to critical revision of the manuscript; all authors read and approved the final manuscript.
Institutional review board statement: The Institutional Review Board of Peking Union Medical College Hospital provided approval for this study (IRB: I-23PJ338).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment. Informed written consent was obtained from the patients for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Bing Xing, MD, Neurosurgeon, Professor, Department of Neurosurgery, Key Laboratory of Endocrinology of Ministry of Health, China Pituitary Adenoma Specialist Council, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, No. 1 Shufuyuan, Dongcheng District, Beijing 100730, China. xingbingemail@aliyun.com
Received: November 22, 2022
Peer-review started: November 22, 2022
First decision: February 14, 2023
Revised: March 1, 2023
Accepted: March 24, 2023
Article in press: March 24, 2023
Published online: April 26, 2023
Core Tip

Core Tip: Although clinicians generally recommend conservative treatment for patients with pituitary adenomas (PAs), surgical treatment is occasionally necessary. Currently, surgical interventions utilized among these patients is poorly studied. This study investigated the surgical interventions utilized for patients with PAs occurring during pregnancy. We found that in the second and third trimesters transsphenoidal PA surgery is a safe and effective approach for emergency conditions arising during pregnancy and may be conducted after a multidisciplinary team evaluation. These strategies may open up new avenues for the treatment of PAs during pregnancy in the future.