Copyright
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 6, 2023; 11(1): 150-156
Published online Jan 6, 2023. doi: 10.12998/wjcc.v11.i1.150
Published online Jan 6, 2023. doi: 10.12998/wjcc.v11.i1.150
Adult focal β-cell nesidioblastosis: A case report
Kui Tu, Li-Jin Zhao, Jin Gu, Department of General Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, Guizhou Province, China
Author contributions: Tu K wrote the article, Zhao LJ revised the article, and Gu J reviewed the medical records and managed follow-up visits; all authors have read and approved the final version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying image.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jin Gu, Doctor, Associate Chief Physician, Department of General Surgery, Affiliated Hospital of Zunyi Medical University, No. 149 Dalian Road, Zunyi City, Zunyi 563000, Guizhou Province, China. 64838050@qq.com
Received: September 1, 2022
Peer-review started: September 1, 2022
First decision: October 24, 2022
Revised: October 27, 2022
Accepted: December 21, 2022
Article in press: December 21, 2022
Published online: January 6, 2023
Peer-review started: September 1, 2022
First decision: October 24, 2022
Revised: October 27, 2022
Accepted: December 21, 2022
Article in press: December 21, 2022
Published online: January 6, 2023
Core Tip
Core Tip: Focal nesidioblastosis is a neuroendocrine disease which is rarely reported in adults and easily confused with insulinoma, and its pathogenesis is still unclear. We report a rare case of adult focal β-cell nesidioblastosis, which was diagnosed as insulinoma before surgery. Increased glucose level after resection of the lesion may assist in the diagnosis of focal β-cell nesidioblastosis, due to intra-pancreatic regulation in focal nesidioblastosis. We also review the related literature. This case report may enhance clinicians' understanding of this disease.