Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 6, 2022; 10(7): 2268-2274
Published online Mar 6, 2022. doi: 10.12998/wjcc.v10.i7.2268
Mixed neuroendocrine-nonneuroendocrine neoplasm of the ampulla: Four case reports
Yang Wang, Zhen Zhang, Cheng Wang, Shi-Hang Xi, Xiao-Ming Wang
Yang Wang, Zhen Zhang, Cheng Wang, Shi-Hang Xi, Xiao-Ming Wang, Department of Hepatobiliary Surgery, The First Affiliated Hospital of Wannan Medical College, Wuhu 241000, Anhui Province, China
Author contributions: Wang Y contribute to data analysis and writing; Zhang Z and Wang C contribute to data collection; Xi SH contribute to manuscript revision; Wang XM contribute to data and manuscript revision; all authors issued final approval for the version to be submitted.
Supported by Funded Project of "Mountain Climbing" Cultivation Project of Yijishan Hospital of Wannan Medical College, No. KPF2019011.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CAREChecklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao-Ming Wang, MD, Chief Doctor, Professor, Department of Hepatobiliary Surgery, The First Affiliated Hospital of Wannan Medical College, No. 2 Zheshan West Road, Wuhu 241000, Anhui Province, China. wxm6901@aliyun.com
Received: July 20, 2021
Peer-review started: July 21, 2021
First decision: October 16, 2021
Revised: October 27, 2021
Accepted: January 25, 2022
Article in press: January 25, 2022
Published online: March 6, 2022
Processing time: 224 Days and 11.4 Hours
Core Tip

Core Tip: Mixed neuroendocrine-nonneuroendocrine neoplasm (MiNEN) is a rare tumor that occurs in the gastrointestinal tract and pancreas. MiNEN occurring in ampulla is extremely rare. We report 4 cases of MiNEN of the ampulla, summarizes these cases and reviews related literature.