Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Feb 26, 2022; 10(6): 2007-2014
Published online Feb 26, 2022. doi: 10.12998/wjcc.v10.i6.2007
Primary duodenal dedifferentiated liposarcoma: A case report and literature review
Nah Ihm Kim, Ji Shin Lee, Chan Choi, Jong Hee Nam, Yoo Duk Choi, Hee Joon Kim, Sung Sun Kim
Nah Ihm Kim, Jong Hee Nam, Yoo Duk Choi, Sung Sun Kim, Department of Pathology, Chonnam National University Hospital, Gwangju 61469, South Korea
Ji Shin Lee, Chan Choi, Department of Pathology, Chonnam National University Hwasun Hospital, Hwasun 58128, South Korea
Hee Joon Kim, Department of Surgery, Chonnam National University Hospital, Gwangju 61469, South Korea
Author contributions: Kim NI, Choi YD, and Kim SS conceptualized the manuscript; reviewed the literature; and interpreted the H&E slides, immunohistochemistry slides, and fluorescence in situ hybridization; Lee JS, Choi C, and Nam JH contributed to the manuscript draft; Kim HJ contributed to the operative performance; all authors read and approved the final manuscript.
Supported by Grant from Chonnam National University Hospital Biomedical Research Institute, No. CRI17004-1.
Informed consent statement: Written informed consent was obtained from the patient for publication of this case report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sung Sun Kim, MD, PhD, Associate Professor, Department of Pathology, Chonnam National University Hospital, No. 42 Jebong-ro, Gwangju 61469, South Korea. succeedsoon@hanmail.net
Received: September 1, 2021
Peer-review started: September 1, 2021
First decision: October 18, 2021
Revised: October 27, 2021
Accepted: January 11, 2022
Article in press: January 11, 2022
Published online: February 26, 2022
Core Tip

Core Tip: Primary dedifferentiated liposarcoma (DDLPS) originating from the duodenum are rare and can be diagnosed based on histology, immunohistochemistry and MDM2 amplification via fluorescence in situ hybridization. Differential diagnoses are required along with consideration of DDLPS.