Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Feb 26, 2022; 10(6): 1981-1990
Published online Feb 26, 2022. doi: 10.12998/wjcc.v10.i6.1981
Surgery and antibiotics for the treatment of lupus nephritis with cerebral abscesses: A case report
Qiong-Dan Hu, Li-Shang Liao, Yong Zhang, Qiong Zhang, Jian Liu
Qiong-Dan Hu, Qiong Zhang, Jian Liu, Department of Nephrology, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China
Qiong-Dan Hu, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50000, Thailand
Li-Shang Liao, Department of Neurosurgery, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China
Yong Zhang, Department of Neurosurgery, Suining First People's Hospital, Suining 629000, Sichuan Province, China
Author contributions: Hu QD and Liao LS contributed equally to this study. Hu QD was the patient’s nephrologist, searched the literature, collected data, wrote, and edited the manuscript; Liao LS was the patient’s neurosurgeon; Liao LS and Zhang Y reviewed the literature and contributed to manuscript drafting; Zhang Q and Liu J were responsible for revision of the manuscript for important intellectual content; all authors issued final approval of the version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jian Liu, Doctor, MD, Chief Doctor, Dean, Professor, Department of Nephrology, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, No.182 Chunhui Road, Longmatan District, Luzhou 646000, Sichuan Province, China. 834300205@qq.com
Received: August 21, 2021
Peer-review started: August 21, 2021
First decision: November 1, 2021
Revised: November 12, 2021
Accepted: January 20, 2022
Article in press: January 20, 2022
Published online: February 26, 2022
Processing time: 186 Days and 5 Hours
Core Tip

Core Tip: Infection is a common complication of systemic lupus erythematosus (SLE) treated with glucocorticoids and immunosuppressants, but multiple cerebral abscesses caused by a rare pathogen are uncommon. Conventional treatment includes surgery and antibiotics. However, due to concerns about SLE exacerbation after the reduction of glucocorticoid and immunosuppressant, and poor tolerability to surgery for multiple cerebral abscesses in patients with SLE, treatment is often difficult, and selection of antibiotics sensitive to rare pathogens is challenging. We report a patient who benefited from individualized surgical treatment of multiple cerebral abscesses, and a multi-antibiotic regimen, with good outcomes.