Retrospective Cohort Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Feb 26, 2022; 10(6): 1795-1805
Published online Feb 26, 2022. doi: 10.12998/wjcc.v10.i6.1795
Multidrug-resistant organisms in intensive care units and logistic analysis of risk factors
Ying Han, Jin Zhang, Hong-Ze Zhang, Xin-Ying Zhang, Ya-Mei Wang
Ying Han, Jin Zhang, Hong-Ze Zhang, Xin-Ying Zhang, Ya-Mei Wang, Infection Control Office, Affiliated Hospital of Hebei University, Baoding 071000, Hebei Province, China
Author contributions: Han Y and Zhang J made equal contributions to the work; Han Y, Zhang J and Zhang HZ designed the study; Han Y, Zhang J, Zhang HZ, Wang YM, Zhang XY and Zhou XL studied; Zhang J and Zhang HZ analyze data and write articles; all authors have read and approved the final manuscript.
Supported by Drug resistance trend analysis and prevention and control of main pathogens in tertiary hospitals of Hebei Provincial Department of health, No. 20210845; and Analysis of drug and drug resistance trend and prevention and control of pathogens in major general hospitals of Baoding science and technology support plan project, No. 17zf79.
Institutional review board statement: The study was reviewed and approved by the Affiliated Hospital of Hebei University Institutional Review Board (Approval No. HDFY-LL-2020-021).
Informed consent statement: Informed written consent was obtained from the patient.
Conflict-of-interest statement: Han Y has received fees for serving as a speaker, Han Y has received research funding from Hebei Provincial Department of Health and Baoding science and technology; Han Y, Zhang HZ, Wang YM, Zhang XY, Zhang J, Zhou XL owns stocks and/or shares in Affiliated Hospital of Hebei University.
Data sharing statement: Corresponding author at hanyingsci@126.com. Participants gave informed consent for data sharing.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jin Zhang, BMed, Attending Doctor, Deputy Director, Doctor, Lecturer, Neurosurgeon, Infection Control Office, Affiliated Hospital of Hebei University, No. 212 Yuhua East Road, Baoding 071000, Hebei Province, China. hanyingsci@126.com
Received: June 22, 2021
Peer-review started: June 22, 2021
First decision: September 1, 2021
Revised: September 15, 2021
Accepted: January 14, 2022
Article in press: January 14, 2022
Published online: February 26, 2022
Processing time: 246 Days and 2.9 Hours
Core Tip

Core Tip: This study described the current situation of multi drug resistant bacteria infection in intensive care unit (ICU) patients, and analyzed the main pathogens of nosocomial infection in ICU and the risk factors of multi drug resistant bacteria infection. The results showed that mechanical ventilation and intubation were the risk factors of multidrug resistant bacterial infection. To provide effective scientific basis for improving the clinical efficacy of antibiotics and scientific strategies for the prevention and treatment of multidrug-resistant bacteria.