Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 26, 2022; 10(36): 13364-13372
Published online Dec 26, 2022. doi: 10.12998/wjcc.v10.i36.13364
Solitary hyoid plasmacytoma with unicentric Castleman disease: A case report and review of literature
Yan-Hui Zhang, Yi-Feng He, Hao Yue, Yue-Ni Zhang, Lei Shi, Bin Jin, Pin Dong
Yan-Hui Zhang, Bin Jin, Pin Dong, Department of Otolaryngology-Head and Neck Surgery, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai 200080, China
Yi-Feng He, Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai 200080, China
Hao Yue, Department of Pathology, Shanghai Cancer Center, Fudan University, Shanghai 200032, China
Yue-Ni Zhang, Lei Shi, NHC Key Laboratory of Molecular Probes and Targeted Diagnosis and Therapy, The Fourth Affiliated Hospital of Harbin Medical University, Harbin 150028, Heilongjiang Province, China
Author contributions: Shi L, Zhang YH and Zhang YN wrote this report; Jin B and Dong P reviewed and revised the manuscript; Zhang YH and Jin B involved in the clinical treatment and follow-up of the patient; Yue H, He YF, Zhang YN and Shi L interpreted the histopathology and radiology; and all authors had made a substantial contribution to this work and approved it for publication.
Supported by Key Program of the Medical Engineering Cross Research Fund of Shanghai Jiao Tong University, No. YG2019QNA55; and Tou-Yan Innovation Team Program of Heilongjiang Province, No. 2019-15.
Informed consent statement: Informed written consent was obtained from the patient for the publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Lei Shi, PhD, Associate Professor, NHC Key Laboratory of Molecular Probes and Targeted Diagnosis and Therapy, The Fourth Affiliated Hospital of Harbin Medical University, No. 766 Xiang’an North Street, Harbin 150028, Heilongjiang Province, China. shilei_0328@vip.sina.com
Received: August 16, 2022
Peer-review started: August 16, 2022
First decision: September 5, 2022
Revised: September 17, 2022
Accepted: December 5, 2022
Article in press: December 5, 2022
Published online: December 26, 2022
Core Tip

Core Tip: In this study, we described the clinical presentations, diagnosis and differential diagnosis, management, outcome, and relative long-term follow-up for a man simultaneously affected with solitary plasmacytoma (SP) of the hyoid bone and unicentric Castleman disease. To our knowledge, this is the first reported case presented with these two rare clinical entities. Besides the comprehensive histopathological examination, 18F-FDG positron emission tomography/computed tomography (CT) and 99mTc-MDP single-photon emission computed tomography (SPECT)/CT were broadly used in our clinical practice of differential diagnosis, disease staging, and follow-up monitoring, highlighting the advantages of nuclear medicine and other imaging techniques in the management of SP in the head and neck. Additionally, the diagnostic process and differential diagnosis of this patient provided valuable educational information to clinicians.